Medication
Common concentrations:
Example doses:
Draw to
— units
= — mL on a U-100 syringe
U-100 Insulin Syringe (1.0 mL / 100 units)
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Enter a dose to preview the syringe draw.
Safety note: Units depend entirely on vial concentration. Do not use this calculator to change your prescribed plan. Confirm your vial’s labeled concentration and syringe type with your pharmacy or clinician before injecting.
Formula (U-100 insulin syringe): Units = (Dose in mg ÷ Concentration in mg/mL) × 100
Free GLP-1 Calculator

Calculate Semaglutide & Tirzepatide Syringe Units

Use this GLP-1 dose calculator to convert your prescribed semaglutide or tirzepatide dose from milligrams (mg) into U-100 syringe units based on your vial concentration.

Using the calculator is simple:

  1. Select your GLP-1 medication.
  2. Choose your vial concentration.
  3. Select your prescribed dose in milligrams (mg).
  4. View the estimated U-100 syringe units and the visual syringe guide.
Important: This calculator is intended only for people who have already received a GLP-1 prescription from a licensed healthcare provider. It does not prescribe a dose, recommend a dose, or replace instructions from your physician, pharmacist, or prescription label.
GLP-1 Basics

What Is a GLP-1 Dose Calculator?

A GLP-1 dose calculator is an online tool that converts your prescribed GLP-1 dose from milligrams (mg) into the number of U-100 syringe units needed based on your vial concentration.

Many people find GLP-1 dosing confusing because prescriptions may reference milligrams (mg), milliliters (mL), and syringe units. This calculator connects those measurements, making it easier to determine the correct amount to draw into a U-100 insulin syringe.

Measurement What It Represents Example
mg Amount of medication 0.25 mg
mL Volume of liquid medication 0.05 mL
Units Markings on a U-100 syringe 5 units
Example: Your prescription may instruct you to inject 0.25 mg of semaglutide, while your syringe is marked only in units. Using your vial concentration, the calculator estimates how many U-100 syringe units correspond to that prescribed dose.
Remember: The calculator estimates syringe units based on the information you enter. Always verify your prescribed dose and vial concentration before preparing an injection.
Calculator Formula

How the GLP-1 mg to Units Calculator Works

The calculator uses a simple dose conversion formula to determine how many U-100 syringe units correspond to your prescribed GLP-1 dose.

Conversion Formula

U-100 Syringe Units = (Dose ÷ Vial Concentration) × 100

This works because a U-100 insulin syringe contains 100 units per 1 mL.

Example Calculation

Suppose your prescribed semaglutide dose is 0.25 mg and your vial concentration is 5 mg/mL.

Step Calculation Result
1 0.25 mg ÷ 5 mg/mL 0.05 mL
2 0.05 mL × 100 5 units

Final Result

A prescribed dose of 0.25 mg from a 5 mg/mL vial equals 5 units on a U-100 syringe.

Important: This example demonstrates the math behind the calculator. Your actual syringe units depend on your prescribed dose, vial concentration, and the syringe type you are using. Always follow your prescription label and your healthcare provider’s instructions.
Semaglutide Schedule

Semaglutide Dosing Schedule

Semaglutide dosing depends on the medication, indication, formulation, and your prescriber’s instructions. Always follow the dosing instructions from your prescriber.

Applies to: Ozempic and Wegovy dosing may differ. Do not use one dosing schedule for the other unless your prescriber specifically instructs you to.

Ozempic Injection Dosing Schedule

Time Period Dose
Week 1 to 4 0.25 mg once weekly
Week 5 to 8 0.5 mg once weekly
Week 9 to 12 Increase to 1 mg once weekly if more glycemic control is needed after at least 4 weeks on 0.5 mg
Week 13 and after Increase to 2 mg once weekly if more glycemic control is needed after at least 4 weeks on 1 mg
Maximum dose 2 mg once weekly

Wegovy Injection Dosing Schedule

Time Period Dose
Week 1 to 4 0.25 mg once weekly
Week 5 to 8 0.5 mg once weekly
Week 9 to 12 1 mg once weekly
Week 13 to 16 1.7 mg once weekly
Week 17 and after Maintenance dose depends on indication
Weight reduction in adults 1.7 mg or 2.4 mg once weekly, with 2.4 mg recommended
If additional weight reduction is clinically indicated After tolerating 2.4 mg for at least 4 weeks, dose may increase to 7.2 mg once weekly
Cardiovascular risk reduction in adults 1.7 mg or 2.4 mg once weekly, with 2.4 mg recommended
MASH with moderate to advanced liver fibrosis 2.4 mg once weekly, or 1.7 mg if 2.4 mg is not tolerated
Maximum dose 7.2 mg once weekly
Important: Semaglutide dosing schedules vary by product and indication. Always use the schedule provided by your prescriber or pharmacist.
Semaglutide Unit Conversion

How to Calculate Semaglutide Units

The calculator above helps estimate how many U-100 syringe units match a prescribed semaglutide dose.

To calculate semaglutide units, you need:

  1. Your prescribed semaglutide dose in mg
  2. Your vial concentration in mg/mL

The table below uses an example concentration of 5 mg/mL.

Prescribed Dose Example Concentration mL to Draw U-100 Units
0.25 mg 5 mg/mL 0.05 mL 5 units
0.5 mg 5 mg/mL 0.10 mL 10 units
1 mg 5 mg/mL 0.20 mL 20 units
1.7 mg 5 mg/mL 0.34 mL 34 units
2.4 mg 5 mg/mL 0.48 mL 48 units
Important: Different vial concentrations produce different unit amounts. Always confirm your dose with your prescription label, pharmacist, or healthcare provider.
Vial Concentration Guide

Does Vial Concentration Matter?

Yes. Vial concentration tells you how many milligrams (mg) of medication are contained in each milliliter (mL) of liquid.

How concentration affects your syringe units:

  • Higher concentration (more mg/mL): Less liquid is needed, so you draw fewer U-100 syringe units.
  • Lower concentration (less mg/mL): More liquid is needed, so you draw more U-100 syringe units.

The examples below show how the same 0.25 mg dose requires a different number of syringe units depending on the vial concentration.

Prescribed Dose Vial Concentration mL to Draw U-100 Units
0.25 mg 2.5 mg/mL 0.10 mL 10 units
0.25 mg 5 mg/mL 0.05 mL 5 units
0.25 mg 10 mg/mL 0.025 mL 2.5 units
Important: Never assume the same number of syringe units applies to every vial. If your vial concentration changes, the number of U-100 units needed may also change—even if your prescribed dose in milligrams stays exactly the same. Always verify your vial concentration before calculating your dose.
Tirzepatide Schedule

Tirzepatide Dosing Schedule

Both Zepbound® and Mounjaro® follow the same gradual dose-escalation schedule. Increasing the dose slowly helps improve tolerability and may reduce gastrointestinal side effects.

Typical dose escalation: The dose is generally increased every 4 weeks only if additional treatment is needed and the current dose is well tolerated.
Time Period Recommended Dose
Week 1 to 4 2.5 mg once weekly
Week 5 to 8 5 mg once weekly
Week 9 to 12 7.5 mg once weekly (if needed)
Week 13 to 16 10 mg once weekly (if needed)
Week 17 to 20 12.5 mg once weekly (if needed)
Week 21 and after 15 mg once weekly (if needed)
Maximum dose 15 mg once weekly
Important: Do not increase your tirzepatide dose unless instructed by your healthcare provider. Remaining on a lower dose for longer may be appropriate if side effects occur or additional dose escalation is not needed.
Tirzepatide Unit Conversion

How to Calculate Tirzepatide Units

A tirzepatide units calculator works similarly to a semaglutide units calculator. The main difference is that tirzepatide has its own prescribed dosing schedule and vial concentrations.

To calculate tirzepatide units, you need:

  1. Your prescribed tirzepatide dose in mg
  2. Your vial concentration in mg/mL

The example below demonstrates common tirzepatide doses using typical vial concentrations.

Prescribed Dose Example Concentration mL to Draw U-100 Units
2.5 mg 10 mg/mL 0.25 mL 25 units
5 mg 10 mg/mL 0.50 mL 50 units
7.5 mg 10 mg/mL 0.75 mL 75 units
10 mg 20 mg/mL 0.50 mL 50 units
15 mg 20 mg/mL 0.75 mL 75 units
Important: These examples are for illustration only. Tirzepatide is available in multiple vial strengths and concentrations, so the number of U-100 syringe units can vary. Always verify your dose using your prescription label or the calculator above before administering any medication.
Dose Conversion Warning

Can You Convert Semaglutide to Tirzepatide?

No. Semaglutide and tirzepatide doses are not directly interchangeable. Although both medications are GLP-1 receptor agonist therapies, they contain different active ingredients, have different mechanisms of action, and follow different dose-escalation schedules.

Example: A 1 mg dose of semaglutide is not equivalent to a 1 mg dose of tirzepatide. Their dosing schedules and therapeutic effects cannot be compared milligram-for-milligram.

Do not use this calculator to convert between medications.

This calculator is designed only to convert a prescribed dose into mL and U-100 syringe units for the medication you have already been prescribed. If you are switching from semaglutide to tirzepatide (or vice versa), contact your prescriber or pharmacist for the correct starting dose and titration schedule.

Dosing Safety

Common GLP-1 Dosing Mistakes to Avoid

GLP-1 dosing errors can happen when people confuse mg, mL, and syringe units. They can also happen when a vial concentration changes, but the same unit amount is reused from an older vial.

Key reminder: Your prescribed dose in mg, the vial concentration, and the U-100 syringe units all need to match.

Mistake 1. Using units from an older vial

If your vial concentration changes, the same number of units may no longer equal the same dose in mg. For example, 10 units from a 5 mg/mL vial is a different medication amount than 10 units from a 10 mg/mL vial. Always check the current vial concentration.

Mistake 2. Confusing mg, mL, and units

These three measurements are related, but they are not interchangeable.

Measurement What It Means Example
mg Amount of medication 0.25 mg semaglutide
mL Liquid volume 0.05 mL
units Syringe marking 5 units

Mistake 3. Using the wrong syringe type

This calculator is designed for U-100 syringes. If you use a different syringe type, the unit markings may not match this calculator. Use the syringe type that your prescriber or pharmacist provided.

Mistake 4. Drawing to the wrong tick mark

Some syringes have small tick marks that can be hard to read. Our visual syringe guide can help, but it does not replace pharmacist instruction. If your calculated amount is very small, ask your pharmacist how to measure it accurately.

Mistake 5. Increasing your dose without medical guidance

Do not increase your GLP-1 dose unless your prescriber tells you to. Many GLP-1 dosing schedules increase gradually to help with tolerability. Taking more than prescribed or increasing too quickly may increase the risk of side effects.

Safety reminder: Always follow your prescription label and pharmacist instructions. The calculator is for educational estimation only.

How to draw your GLP-1 dose into the syringe

Here’s how to carefully draw the medication to the calculated unit mark on the syringe:

  • Clean the top of the vial. Remove the vial cap if this is the first use. Wipe the rubber stopper with an alcohol swab and let it dry.
  • Check your calculated unit amount. Look at the calculator result and identify the exact unit mark on your U-100 syringe. Make sure you are using the correct vial concentration and prescribed dose.
  • Pull air into the syringe. With the needle still capped or before inserting it into the vial, pull the plunger back to draw air into the syringe. In many vial-based injections, the amount of air drawn into the syringe matches the amount of medication you plan to withdraw. Follow your pharmacist’s instructions if they told you something different.
  • Insert the needle into the vial. Place the vial on a flat surface or hold it steady. Insert the needle straight through the center of the rubber stopper.
  • Push the air into the vial. Press the plunger to push the air into the vial. This can help make it easier to withdraw the medication.
  • Turn the vial and syringe upside down. Keep the needle tip inside the liquid. Make sure the needle opening stays below the surface of the medication so you do not pull in air.
  • Slowly pull back the plunger. Pull the plunger back until the medication reaches your calculated unit mark. Go slowly so you can measure accurately.
  • Check for air bubbles. If you see air bubbles, keep the needle in the vial and gently tap the syringe so the bubbles rise toward the top. Then slowly push the bubbles back into the vial and pull the medication back to the correct unit mark.
  • Confirm the final dose at eye level. Hold the syringe so the markings are easy to read. Check that the top of the plunger lines up with the calculated unit mark. Reading the syringe at eye level helps prevent drawing too much or too little.
  • Remove the needle from the vial. Once the correct amount is in the syringe and the dose is confirmed, carefully remove the needle from the vial. Avoid touching the needle or letting it touch any surface.

If you cannot remove air bubbles, cannot clearly read the syringe, or are unsure whether you drew the right amount, do not inject the medication. Ask a friend or family member for help.

GLP-1 Dose Calculator FAQs

It depends on the vial concentration. For example, if your semaglutide concentration is 5 mg/mL, then 0.25 mg equals 5 units on a U-100 syringe. If your vial has a different concentration, the number of units will be different.
At 5 mg/mL, 0.5 mg equals 10 units on a U-100 syringe.
At 5 mg/mL, 1 mg equals 20 units on a U-100 syringe. If your vial is 10 mg/mL, 1 mg would equal 10 units instead.
At 10 mg/mL, 2.5 mg tirzepatide equals 25 units on a U-100 syringe. If your concentration is different, your units will be different.
At 10 mg/mL, 5 mg tirzepatide equals 50 units on a U-100 syringe. Always calculate based on the concentration in your current vial.
No. Milligrams and units are not the same thing. Milligrams measure the amount of medication. Units on a U-100 syringe measure liquid volume. You need the vial concentration to convert between mg and syringe units.
U-100 means there are 100 units in 1 mL of liquid. On a U-100 syringe, 10 units equals 0.1 mL, 50 units equals 0.5 mL, and 100 units equals 1 mL.
There is no FDA-approved single 60 mg tirzepatide dose vial for Zepbound or Mounjaro. Some compounded tirzepatide products may be labeled with higher total vial amounts, such as 30 mg, 40 mg, or 60 mg per vial. If you have a vial labeled 60 mg, check the concentration, total volume, dosing instructions, and pharmacy source with your prescriber or pharmacist before using it.
For FDA-approved tirzepatide products, the highest recommended adult dose is 15 mg once weekly.
Do not inject a 30 mg tirzepatide dose unless a licensed prescriber has specifically instructed you to do so and verified the dose. If your vial says 30 mg, that may refer to the total amount of medication in the vial, not the dose you should inject at one time. Check the label carefully and contact your prescriber or pharmacist before injecting.
No. This calculator should not be used to convert semaglutide to tirzepatide or tirzepatide to semaglutide. These medications are not directly interchangeable. Talk to your prescriber if you are switching medications. Related Blogs:
No. Compounded drugs are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness, or quality before marketing. If you use compounded semaglutide, it should be prescribed by a licensed clinician and dispensed by a legitimate pharmacy.
Contact your prescriber, pharmacist, Poison Control, or emergency care, depending on your symptoms. Do not wait if you have severe vomiting, severe abdominal pain, fainting, dehydration, trouble breathing, or other urgent symptoms.
No. This calculator should not be used to create or decide tirzepatide reconstitution instructions. 
No. This calculator should only be used for semaglutide and tirzepatide.
Safety First

Safety Reminder When Using a GLP-1 Dose Calculator

This GLP-1 dose calculator is provided for educational purposes only. It helps estimate U-100 syringe units based on the information you enter, but it does not prescribe medication, recommend a dose, or replace professional medical advice.

Before every injection, verify all of the following:

  • You are using the correct GLP-1 medication.
  • The vial concentration (mg/mL) matches your prescription.
  • You are using the correct U-100 syringe.
  • The calculated syringe units match your prescribed dose.
  • Your medication has been stored and prepared according to the manufacturer’s instructions.

Always follow your healthcare provider’s instructions.

If you have questions about your prescribed dose, missed doses, side effects, switching medications, injection technique, or medication storage, contact your physician or pharmacist before administering your injection.

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