Lantus can be used in adults and children ages 6 and older for type one or type two diabetes. Tresiba can be used in adults and children aged 1 and older for type one and type 2 diabetes. Both are considered long-acting insulin with no identifiable peak; therefore their use is most consistent with the pancreas’s basal production of insulin throughout the day.
Administered by either the SoloStar injection pen or a vial and a syringe it can be used once a day. It is recommended to administer it at the same time every day. Lantus can continue to work throughout the day and the night, from 12-24 hours. Lantus is indicated to improve glycemic control in adults and in pediatric patients with type one diabetes over the age of six.
Tresiba can be taken by injection once a day and is available in a flex pen or a vial and syringe. It is recommended you use Tresiba at the same time every day, but if an adult misses a dose, they can take their next dose as soon as they remember. Tresiba offers a little more dosing flexibility compared to other long-acting insulin preparations. If a dose is missed, just ensure that eight hours are between each dose.
Key differences between Lantus and Tresiba
|Must be 6 years or older||Must be 1 year or older|
|Insulin glargine||Insulin degludec|
|Manufactured by Sanofi||Manufactured by NovoNordisk|
|Type 2 diabetes in adults, type one over 6||Type 1 or type 2 diabetes|
|Lasts up to 24 hours||Lasts up to 42 hours|
|Must be taken at the same time each day||Administration times can vary|
In addition to the duration of action, chemical make-up, and age range in which users can begin using this medicaiton, there are a few other key differences. While any preparation of insulin has a risk of hypoglycemia or low blood sugar, Tresiba has been shown to be less likely to cause these events. Cost is also a likely factor when considering differences in your diabetes medications. Lantus is generally cheaper than Tresiba.
Both Lantus and Tresiba
The side effects are very similar for both Tresiba and Lantus. Some side effects can be an emergency, while others just require close monitoring and a discussion with your doctor.
Common side effects
Emergency side effects
|Swelling of the hands and feet||Hypoglycemia|
|Weight gain||Trouble breathing|
|Injection site irritation||Swelling of the face, lips, and mouth|
|Skin pitting at the injection site||Rash all over the body|
|Skin thickening at the injection site||Extreme dizziness or confusion|
|Low blood potassium levels|
Hypoglycemia. The most common side effect of any insulin is hypoglycemia or low blood sugar which can be very serious and even life-threatening. Commonly people will experience symptoms prior to an episode of hypoglycemia which includes:
- fast heartbeat
- blurred vision
To remain safe while on insulin therapy, it is essential that you track your blood sugar and know what to do in the event of a hypoglycemia event. If you experience any of the above symptoms, you should immediately check your blood sugar levels, and eat a sugary snack.
Do not mix either Lantus or Tresiba with any other insulins or solutions. Discuss all your other medications with your doctor to ensure none of the medications you are taking could potentially interact with your long-acting insulin. You should also avoid alcohol while using long-acting insulins as they can complicate the detection of hypoglycemic events.
You should avoid taking TZDs while using Tresiba as it can cause heart failure in those who do not already have heart failure. Additionally, if you become more active, drastically change your diet, or become sick, you may need to discuss dose adjustments with your doctor.
Do not share needles or insulin pens or syringes with anyone else. You should not reuse your own needles, disposing of them after each use. To prevent infections, you should change and rotate your injection sites. This can also reduce your risk of getting pitted or thickened skin. You should avoid reusing the same injection sites for your insulin.
Your dosage can vary widely based on your own insulin needs. Your doctor will evaluate your laboratory values in conjunction with your current medication regimen to determine what dosing is the best option for you.
Lantus comes in two preparations, a prefilled pen, or a vial. Options for administration include vial and syringes or the SoloStar Lantus pen. Lantus is most commonly available in a 100 unit per milliliter vial which is a total of 10 milliliters. The prefilled pen comes as 100 units per milliliter in a 3-milliliter pen.
Tresiba also comes in two preparations, like Lantus. Tresiba can be administered from a vial with syringes, or the FlexTouch pen. The vial comes in two concentrations, 100 or 200 units per milliliter. The Tresiba FlexTouch pen comes as 100 units per milliliter in a 3-milliliter prefilled syringe. Once opened, the FlexTouch pen can last up to eight weeks of use if it is refrigerated or kept at room temperature.
Frequently Asked Questions
How do I take Lantus?
Lantus is an injection that will be administered under this skin it’s called a subcutaneous injection which can either be administered via the Lantus SoloStar pen or with a vial and a syringe.
Can Lantus cause weight gain?
Weight gain can occur with any insulin therapy which includes Lantus following a healthy diet and exercise program can help you with weight control
Are there any side effects with Lantus?
The most common side effect of any insulin including Lantus is low blood sugar which can be serious or life-threatening. other serious reactions include allergic reactions. seek medical attention immediately if you develop a rash over your body trouble breathing sweating swelling of your tongue throat or face shortness of breath or extreme drowsiness or confusion.
Can I mix Lantus with other insulin?
No, you should not mix Lantus with any other insulin or other solutions it may not work as intended and you could lose blood sugar control
I take mealtime insulin will I need to change my dose while I’m on Lantus?
You should discuss with your doctor what if any adjustments you should make to your insulin regimen when you add Lantus
Is there a generic version of Lantus?
No. There is only one Lantus preparation. There are other biosimilars on the market, although they may have a slightly different action than Lantus. Talk with your doctor to determine what long-acting insulin may be best for you.
What is Tresiba?
Tresiba is a long-acting insulin that is used to control high blood sugar in adults and children as young as one year of age with diabetes.
Do I have to take Tresiba at the same time every day?
Adults can take Tresiba at any time of the day. It is up to you to decide which time and place work best for you. Children must take their dose at the same time every day. Adults who miss or delay a dose should take their dose as soon as they remember and then continue with their regular dose schedule. You should ensure that there are at least eight hours between your doses. If a child misses a dose, you should call their health care provider and monitor blood sugar more closely until the next scheduled dose.
Does Tresiba interact with other drugs?
It is important to discuss any medications you take with your health care provider including any prescription and over-the-counter drugs. Your dose of Tresiba may be changed if you take other medications, and doses of other medicines can be changed as well. Heart failure can occur in some people who take TZDs. It can develop even if you’ve never had heart problems before if you already have heart problems it can worsen them so tell your health care provider if you have any new or worsening symptoms of heart failure like shortness of breath tiredness or swelling of your ankles and feet.
Can Tresiba be used with other diabetes medications?
It can be used in combination with diabetes pills or short-acting insulin.
How do I take Tresiba?
Tresiba is administered by subcutaneous injection once a day. you should discuss with your doctor how to take Tresiba based on your individual insulin needs. if you believe you may need to change your dosing because of new medicines stress changing your diet or exercise you need to consult with your health care provider. do not make any changes to your dose or the type of insulin that you’re using unless your health care provider tells you to
Can children take Tresiba?
Tresiba is the only long-acting insulin that’s approved for both type 1 and type 2 diabetes in children as young as one-year-old.
How is Tresiba dispensed by a pharmacy?
Tresiba is available in three preparations:
|100 units/milliliter||200 units/milliliter||100 units/milliliter|
|FlexTouch (5 pens/pack)||FlexTouch (3 pens/pack)||Multi-dose 10mL vial|
What should I avoid while taking Tresiba?
You shouldn’t drive or operate heavy machinery until you know how Tresiba affects you. you also shouldn’t drink alcohol or use prescription or over the counter medications that may alcohol
What are the possible side effects of using Tresiba?
The most serious and potentially life-threatening side effects include low blood sugar, low blood potassium, and heart failure.