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Buy Tresiba Insulin Online from Canada

Insulin is a hormone naturally produced by the body that helps regulate blood sugar levels.

People with type 1 diabetes do not produce enough insulin, while people with type 2 diabetes may not use insulin effectively.

Tresiba contains insulin degludec, an ultra-long-acting basal insulin analog developed by Novo Nordisk.

What is Tresiba?

Tresiba (insulin degludec) is a long-acting insulin that lowers blood glucose levels for adults with either type 1 or type 2 diabetes mellitus. It begins to start working several hours after injection and continues to working evenly up to 24 hours.

Tresiba is available in two forms: single multi-dose vial or single-patient-use FlexTouch pen.

The two pens come in two different strengths:

Tresiba FlexTouch U-100 (100 units/mL) containing 300 units of insulin
Tresiba FlexTouch U-200 (200 units/mL) containing 600 units of insulin

TRESIBA USAGE & STORAGE

How is Tresiba used?

Follow instructions as directed by your doctor or pharmacist. Read labels, medication guides, and information sheets to familiarize yourself with this medication.

A medical professional will instruct you on how to administer your insulin.

Tresiba is injected under the skin (subcutaneously) once a day.

The injection pen has a dose counter that decreases after every application.

When using insulin you should be aware of symptoms of low blood sugar (hypoglycemia).

Symptoms include irritability, hunger, confusion, dizziness, anxiety, and shakiness. Treat hypoglycemia by eating a sugary snack or beverage such as jelly beans, hard candies, raisins, crackers, juice, or non-diet soda.

In severe cases, diabetics can lose consciousness from hypoglycemia. Your doctor may prescribe a glucagon kit if this happens. Familiarize yourself with it and instruct friends and family on how to administer the glucagon injection if you pass out. It is hazardous to consume anything orally if this happens, as it could lead to choking.

Also, pay attention to signs of high blood sugar (hyperglycemia). Symptoms may include increased urination and thirst.

Factors such as stress, illness, alcohol, exercise, skipping meals, or surgery can impact blood sugar levels. Consult your doctor before modifying your insulin dosage and schedule.

Tresiba should be used as part of an insulin treatment program. Patients should also make dietary changes, manage their weight, and exercise according to their doctor’s instructions.

Dosing Information

Tresiba for Patients with Type 1 Diabetes

The dose should be individualized based on the patient’s needs. Tresiba should be used in combination with rapid or short-acting insulin.

Tresiba for Patients with Type 2 Diabetes

Initial dose: 10 units injected once per day.
dosage should be adjusted based on patients’ metabolic needs, blood glucose results, and glycemic goals. Dose increments should not be made sooner than 3-4 days.

When adjusting your Tresiba insulin regimen, you should also adjust the dosage for anti-diabetic medications and short-acting insulin.
closely monitor blood glucose levels in order to minimize hypoglycemia, especially when adjusting your insulin regimen

Insulin-native patients

Initial dose: 1/3 to 1/2 the total daily dose injected
Usually, the total daily dose is 0.2-0.4 units of insulin per kg of body weight

Current insulin users

• Initiate the same scheduled injection of long-acting or intermediate-acting insulin
• Monitor blood glucose levels to minimize the effects of hypoglycemia
• Your dosage may need to be adjusted based on your blood glucose levels, metabolic needs, and glycemic goals
• Dose increases should happen no sooner than 3-4 days
• When changing your insulin regimen, you may need to adjust your short-acting insulin as well

How to store Tresiba?

Do not store insulin near a cooling element or freeze. Insulin that has been previously frozen should be discarded.

Keep insulin away from direct light or heat.

Storing unused/unopened Tresiba:

• Keep refrigerated until expiration date on label
• Store at room temperature and use within 56 days (8 weeks)

Storing in use/opened Tresiba:

• Keep refrigerated until the expiration date or store at room temperature for up to 56 days (8 weeks)
• Do not store the injection pen with a needle attached
• Do not use insulin if it has changed colors or appears cloudy. Contact your doctor if you believe your medication is compromised.
• Keep medication away from children or pets.

Discarding medication

Place used needles and syringes in a puncture-proof “sharps” container
Do not throw medication into household trash or down wastewater (i.e., sink, toilet)

SIDE EFFECTS

As with any insulin, side effects may occur. Tresiba may cause mild or severe side effects, and the lists do not provide all of them.

For more information on possible side effects, speak to your doctor or pharmacist, who can also provide information on how to deal with them.

Most side effects are temporary and disappear within a few days or weeks. If the symptoms are severe, consult your doctor immediately.

Mild Side Effects

Tresiba may cause mild side effects, which may include:

• headache
• low blood sugar (hypoglycemia)
• diarrhea
• weight gain
• flu-like symptoms (abdominal cramps, fever, chills, vomiting)
• upper respiratory infections (i.e., common cold)

Less mild side effects include:

• injection site reactions such as swelling, itchiness, redness, or pain
• lipodystrophy (pitting or thickening of the skin at the injection site)
• swelling in legs, feet, or ankles

These side effects have occurred in less than 5% of participants in clinical studies

Serious Side Effects

Serious side effects may occur when taking Tresiba. Contact your doctor immediately if you experience serious side effects or 911 if you feel the symptoms are serious and believe it’s a medical emergency.

Serious side effects include:

• severe allergic reaction
• severe hypoglycemia (extremely low blood glucose levels)
• hypokalemia (low level of potassium in the blood)

Side Effects in Children

Side effects are similar between children and adults. Children may have more complications dealing with hypoglycemia or low blood sugar levels.

Clinical studies have shown that children with type 1 diabetes had shown hypoglycemia to be experienced more in children than adults. During a 1 year trial, 17.8% of children reported hypoglycemia while taking Tresiba, in contrast to adults with 12.3%.
Tresiba Side Effects in Detail

Allergic Reaction
As with taking any medication, patients should be aware of their drug allergies and if they are allergic to any ingredients.

Mild allergic reactions include:

• itchiness
• skin rash
• flushing (redness and warmth of skin)

Severe allergic reactions may include:

• swelling of the tongue, mouth, or throat
• difficulty speaking
• swelling under the skin (eyelids, lips, feet or hands)
• difficulty breathing/wheezing

Seek medical attention immediately if you feel you are experiencing a severe allergic reaction. Call 911 if you feel they are life-threatening. Speak to your doctor about what to do if you experience a severe allergic reaction.

Weight Loss or Weight Gain

Weight gain is a common side effect when taking insulin, including Tresiba. Since insulin assists the liver, muscle, and fat cells in removing sugar from the blood and storing it for future use, over time, this may lead to weight gain.

Studies that included patients with type 1 diabetes taking Tresiba found that the average patient gained 4 pounds over a period of 1 year. Patients with type 2 diabetes gained an average of 6.6 pounds in 1 year.

Speak to you doctor if you have concerns about weight gain. A healthy diet and regular exercise may be recommended along with your treatment.

Inform your doctor if you are taking thiazolidinedione (THZ) which include rosiglitazone (Avandia) and pioglitazone (Actos) . When used in combination with insulin, it can lead to heart failure, and weight gain is usually a symptom.

If you are unexpectedly losing weight while taking Tresiba, inform your doctor so they can examine why this is happening. This may require an adjustment to your insulin dosage.

Vision Complications

While insulin does not cause side effects related to the eyes, diabetes itself can.

If blood sugar levels are not controlled for a long period of time then this may result in developing problems such as glaucoma, cataracts or diabetic retinopathy (damage to the retina in the back of your eye). Get your eyes regularly checked to ensure you are not susceptible to any of these problems.

Hypoglycemia may also affect your eyes, causing blurred vision.

Hypoglycemia

Hypoglycemia (low blood sugar) is a common side effect of taking any insulin medication.

Several factors may lead to hypoglycemia, such as consuming alcohol, exercise more than usual or skipping meals. It also important to note that hyperglycemia (high blood sugar levels) or hypoglycemia (low blood sugar levels) can be a result of changes in your treatment such as new dosage, introducing a new insulin or injecting into areas that are pitted or thickened.

Clinical Studies

In a 1 year clinical study with patients having type 1 diabetes and taking Tresiba, it found that 12.3% had an episode of severe hypoglycemia
A 1 year clinical study including patients with type 2 diabetes taking Tresiba found that 0.3% of adults experienced at least one episode of hypoglycemia
In another study, 4.5% of adults with type 2 diabetes experienced at least one episode of hypoglycemia.

Another study showed that 4.5% of adults with type 2 diabetes had also experienced severe hypoglycemia. In this study, participants were also taking other medications, including oral medications and insulin aspart (i.e., NovoLog, Fiasp).

Symptoms of hypoglycemia may include:

• anxiety
• hunger
• shakiness
• sweating
• irritability
• heart palpitations
• hunger
• nausea
• dizziness

Symptoms of severe hypoglycemia may include:

• difficulty concentrating
• slurred speech
• weakness
• argumentative or irrational behavior
• coordination problems

If hypoglycemia is not looked after, it can lead to more serious complications such as seizures, coma, or even death.

If you feel you are experiencing symptoms of hypoglycemia, consume a glucose tablet; a sugar snack such as jelly beans, raisins, candy, fruit juice or soda (non-diet).

Doctors may prescribe a glucagon kit for patients experiencing severe hypoglycemia. This kit is used if an individual experiences a loss of consciousness and cannot take sugar orally. In addition to patients learning when to administer it, friends and family should also be told how and when to use it.

Blood glucose levels should be tested regularly to help detect the possible onset of hypoglycemia.

Hypokalemia (low potassium levels)

Hypokalemia occurs when patients experience low potassium levels in the blood. This side effect can happen when taking any insulin, including Tresiba.

Symptoms of hypokalemia may include:

• constipation
• fatigue
• irregular heartbeat
• muscle weakness
• muscle cramps
• thirst
• urinating more often

Consult your doctor if you experience symptoms of hypokalemia. Your doctor may want to test potassium levels in your blood.

WARNINGS & PRECAUTIONS

Speak to your doctor before taking Tresiba to discuss risks, safety and how to manage side effects. Discuss any existing medical conditions especially if you have any heart, kidney or liver problems; are pregnant or breast feeding.

Do not inject Tresiba into skin that is tender, bruised, pitted, lumpy, scaly, thickened, or damaged.

Never share injection pens with others, as this can lead to the spreading of infections or disease.

Before taking Tresiba, make sure you are not allergic to insulin degludec or any ingredients contained in this medication.

Tresiba should not be given to children under the age of one.

Inform your doctor if you are pregnant or breastfeeding. Controlling diabetes during pregnancy is important since high blood sugar levels can affect both mother and baby. Be sure to follow your doctor’s instructions on taking Tresiba during pregnancy.

It is unknown whether Tresiba insulin passes through breastmilk or how it affects children who are breastfed. Speak to your doctor about the benefits and risks associated with taking Tresiba while breastfeeding.

Let your doctor know if you are taking any other prescription medication, over-the-counter drugs, herbal supplements, or vitamins, as they may interact with your treatment.

Drug Interactions

Taking other drugs, vaccines, or even foods can impact how the drug works.

Possible drug interactions may include but are not limited to:

• thiazolidinediones.
• antidepressants.
• fluoxetine (Prozac, Sarafem)
• isocarboxazid (Marplan)
• monoamine oxidase inhibitors (MAOIs) such as phenelzine (Nardil)
• methylprednisolone
• prednisone
• HIV medications
• atazanavir (Reyataz)
• darunavir (Prezista)
• fosamprenavir (Lexiva)
• ritonavir (Norvir)
• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• exenatide (Byetta, Bydureon)
• linagliptin (Tradjenta)
• liraglutide (Victoza, Saxenda)

The list above does not include all possible drugs. Your doctor or pharmacist should provide more information on possible drug interactions with Tresiba.

You may not be prescribed Tresiba if you have existing medical conditions or based on other factors, including:

Tresiba may cause patients to experience low blood sugar levels. If you already have kidney or liver complications, your doctor may need to adjust your treatment. Speak to your doctor about what you should be aware of when taking insulin with your pre-existing complications.

Alcohol may lead to hypoglycemia since it lowers blood sugar levels. Speak to your doctor about the effects of alcohol on diabetes.

Ordering Information

Prescription and Pharmacy Information

Tresiba is a prescription insulin medication.

A valid prescription from a licensed healthcare provider is required before Tresiba can be dispensed.

Prescription orders are reviewed according to pharmacy processing requirements before fulfillment.

Products may be dispensed through licensed pharmacy partners located in Canada or other international fulfillment locations depending on product availability.

Pharmacist consultation may be available through participating pharmacy partners when appropriate.

Patients should consult their healthcare provider or pharmacist regarding insulin use, blood glucose monitoring, dose adjustments, storage, and treatment goals.

Shipping, Storage, and Monitoring Information

Tresiba is a temperature-sensitive medication.

Special packaging may be used to help maintain recommended storage conditions during transit.

Shipping timelines may vary depending on destination, pharmacy source, product availability, weather conditions, and carrier service levels.

Upon delivery, inspect the product and store it according to the product storage instructions.

Store unopened Tresiba in the refrigerator between 36°F and 46°F, or 2°C and 8°C.

Do not freeze Tresiba. Do not use insulin that has been frozen, exposed to excessive heat, appears cloudy, contains particles, or has changed color.

After opening, follow the storage instructions provided with your specific Tresiba product.

Patients using Tresiba should monitor blood glucose levels as directed by their healthcare provider. Changes in insulin dose, meals, exercise, illness, stress, or other medications may affect blood sugar control. Do not change your insulin dose or schedule without medical guidance.

Buy Canadian Insulin Information

Buy Canadian Insulin helps customers submit prescription order requests for Tresiba through participating pharmacy partners.

Product availability, pharmacy source, dispensing location, pricing, and shipping timelines may vary depending on order details and prescription review requirements.

Customers may review available pricing and quantity options during checkout before placing an order.

Eligible first-time customers may use coupon code FIRST10 during checkout, subject to current promotional terms and conditions.

Customer support is available for questions related to prescription submission, order processing, shipping information, product availability, and account support.

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

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Saturday-Sunday: 9am – 5pm CST

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