Apidra SoloStar Pen 100 Units / mL
Apidra SoloStar Pens
Insulin Glulisine
Select product strength & quantity:

Prescription Required.

Product of Canada.

Express Ships from Canada.

Prescription Required.
Product of Canada.
Express Ships from Canada.

How Apidra SoloStar 100IU/ml Injectable Pens work

The Apidra Solostar 100IU/ml injectable pen is a rapid acting insulin that begins working 10 to 20 minutes after application. Similar to insulin produced in the body as it allows glucose into fat cells and muscles to produce energy in addition to blocking glucose release from the liver.

The Apidra Solostar 100IU/ml injectable pen is used to improve blood sugar levels in those with type 1 and type 2 diabetes. This fast-acting insulin effectively lowers blood sugar levels after mealtime and can greatly reduce the chances of developing serious diabetes conditions.

This medication is typically prescribed with long-acting type insulin medications or other diabetes medications. Your nurse or doctor will demonstrate the correct way to inject this insulin subcutaneously (under the skin). Part of your diabetes regimen should include regular exercise, healthy diet and weight loss.

Track your blood sugar levels regularly and be sure to share them with your doctor so they can adjust your dosage accordingly.

Side effects

Common side effects with using Apidra Solostar pens include:

  • allergic reactions
  • injection site reactions
  • itching and rash
  • lipodystrophy
  • weight gain
  • hard lumps (lipodystrophy)
  • swelling

To avoid any side effects

  • always inject the correct dose
  • do not skip meals
  • monitor your blood sugar levels regularly
  • avoid drinking excessively
  • have regular meals

If you are experiencing low blood sugar levels (hypoglycemia) do not use this medication. Alert your doctor if you are having any problems with your liver, kidney and heart.

It is unknown if insulin glulasine is excreted through breast milk. There are limited studies that have shown that this medication can harm a developing baby during pregnancy. Your doctor will assess your health and risks before prescribing it as they may need to adjust the dosage amount.

This insulin medication does not pass through breast milk and is not harmful to the baby.

Interaction with other medications

You may need to adjust insulin glulasine dosages as there are a number of substances which can affect glucose metabolism.

Substances that may lower blood glucose levels and lead to hypoglycaemia include:

  • angiotensin
  • ACE inhibitors
  • disopyramide
  • fluoxetine
  • fibrates
  • monoamine oxidase inhibitors (MAOIs)
  • pentaoxifylline
  • propoxyphene
  • salicylates
  • sulphonamide antibiotics
  • oral antibiotics

Substances that may reduce glucose lowering activity include:

  • corticosteroids
  • danazol
  • diazoxide
  • glucagon
  • diurectics
  • isoniazid
  • phenothiazine derivatives
  • somatropin
  • sympathomimetic products (epinephrine, salbutamol, terbutaline)
  • thyroid hormones
  • oestrogens
  • progestins (i.e. oral contraceptives)
  • protease inhibitors
  • atypical antipsychotic products (ie clozapine and olanzapine)

Alcohol, lithium salts, beta-blockers and clonidine may weaken blood glucose lowering activity from the insulin.

Warnings and Precautions for Apidra SoloStar Pens

Hypoglycemia Risk

Apidra can cause low blood sugar (hypoglycemia), especially if the dose is too high, meals are skipped, or after intense exercise. Symptoms include dizziness, sweating, confusion, and shakiness. Always carry a source of fast-acting sugar and monitor blood sugar levels regularly.

Hyperglycemia and Diabetic Ketoacidosis

Inadequate dosing or discontinuation, especially in type 1 diabetes, can lead to high blood sugar (hyperglycemia) and diabetic ketoacidosis, a potentially life-threatening condition. Be aware of symptoms like excessive thirst, frequent urination, and nausea.

Insulin Allergy

Immediate allergic reactions to insulin, including Apidra, can occur. Symptoms may include rash, shortness of breath, rapid heartbeat, and swelling. Seek immediate medical attention if you experience these symptoms.

Injection Site Reactions

Rotate injection sites within the same region to reduce the risk of lipodystrophy (skin thickening or pits at the injection site) and localized cutaneous amyloidosis (skin with lumps).


All insulins, including Apidra, can cause a significant decrease in potassium levels in the blood. Monitor potassium levels in patients at risk of hypokalemia and manage as clinically indicated.

Heart Failure and Cardiovascular Risks

Use caution in patients with heart failure or other cardiovascular conditions, as insulin therapy may cause fluid retention and heart failure exacerbation.

Renal or Hepatic Impairment

Patients with kidney or liver impairment may require lower doses of Apidra, as these conditions can affect insulin metabolism.

Drug Interactions

Certain medications can interact with Apidra, affecting blood sugar levels. Inform your healthcare provider about all medications, supplements, and herbal products you are taking.

Pregnancy and Breastfeeding

Consult your doctor before using Apidra if you are pregnant, planning to become pregnant, or breastfeeding. Insulin needs may change during pregnancy and lactation.

Pediatric Use

While Apidra can be used in children, doses and administration must be carefully monitored by a healthcare provider.

Sharing of Insulin Pens

Do not share your Apidra SoloStar Pen with others, even if the needle is changed, to avoid risk of infection.

Proper Use and Handling:

Ensure proper use of the SoloStar Pen for accurate dosing. Do not use if the insulin is cloudy, colored, or contains particles.

Travel Considerations

When traveling, keep Apidra at the correct temperature and carry a doctor’s note for airport security.


Storage (unopened):

  • Refrigerate until expiration date
  • Keep in a cool temperature (bellow 77 F) and use within 28 days.

Storage (opened):

  • Store vial in refrigerator or at cool temperature and use within 28 days
  • Do not store Apidra injectable pen with needle attached
  • Do not use medication if it looks colorless, cloudy or like it has particles in it
  • Contact your pharmacist for new medicine if you feel it is spoiled.

Quick Tips when taking Apidra SoloStar Pens

  • Use this medication 15 minutes before mealtime or 20 minutes after starting your meal
  • Rotate injection sites regularly to prevent hard lumps or other skin irritations on the same site
  • Always carry a sugary snack such as fruit juice or sweets if you experience hypoglycemia (cold sweats, tremors, weakness or anxiety)
  • Monitor blood sugar levels regularly as Hypoglycemia is a common side effect
  • Do not use if colorless, clear or contains particles
  • For faster results and better absorption, inject below the skin of the abdomen
  • Opened cartridges/vials are good for up to 4 weeks at room temperature, unopened vials should be refrigerated between 2°C–8°C.

Frequently Asked Questions

Apidra SoloStar is a rapid-acting insulin pen used to control high blood sugar in adults and children with diabetes.

Inject Apidra subcutaneously as directed by your healthcare provider, typically within 15 minutes before a meal or within 20 minutes after starting a meal.

Yes, it’s suitable for both type 1 and type 2 diabetes.

Store unused pens in the refrigerator; once in use, keep at room temperature for up to 28 days.

Take the missed dose as soon as you remember, but never double up doses. Consult your healthcare provider for specific advice.

Yes, but keep it at the correct temperature and carry a doctor’s note for airport security.

No specific foods need to be avoided, but follow a balanced diet as recommended for diabetes management.

Common side effects include hypoglycemia, injection site reactions, and allergic reactions.

Consult your doctor as insulin needs may change during pregnancy.

Alcohol can affect blood sugar levels; consult your healthcare provider for guidance.

Dispose of used pens in a sharps container according to local regulations.

Yes, under the guidance of a healthcare provider.

Consume fast-acting carbohydrates and monitor your blood sugar levels. Seek medical attention if symptoms persist.

No, sharing pens can lead to serious infections.

Dose adjustments should only be made under the guidance of a healthcare provider.

An overdose can lead to severe hypoglycemia. Seek immediate medical attention.

Any change in insulin should be made cautiously and only under medical supervision.

Apidra is a rapid-acting insulin, acting faster than regular insulin but with a shorter duration.

Regularly monitor blood sugar levels, follow your diabetes management plan, and consult your healthcare provider for any concerns.

Consult your healthcare provider as dose adjustments may be necessary.

Since this medication contains insulin glulisine it needs to be consumed within 15 minutes of having a meal. You may not be on a regular eating or dosing schedule. If you miss a dose do not use two at the same time.

Contact the Poison Help Line at 1-800-222-1222 or seek medical attention immediately as it can lead to life-threatening hypoglycemia. If you are experiencing symptoms such as drowsiness, confusion, numbness, tingling in your mouth, trouble speaking, blurred vision, muscle weakness, seizures or loss of consciousness – seek medical help.

  • Avoid driving or operating machinery
  • Avoid dosage errors. Be sure to check labels prior to injecting insulin.
  • Avoid drinking alcohol as it can lower blood sugar levels and interfere with medication

Apidra Insulin Medications

This page is for informational purposes and does not replace professional medical advice. Always consult with your healthcare provider for personalized guidance and instructions.