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Bupropion SR Bupropion HCl
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What is Bupropion?

Bupropion is an atypical antidepressant medication primarily used to treat major depressive disorder and seasonal affective disorder. Unlike traditional SSRIs, Bupropion works by inhibiting the reuptake of dopamine and norepinephrine in the brain, helping to restore chemical balance and improve mood. It’s also prescribed as a smoking cessation aid under the brand name Zyban.

Fact Category Fact Details
Generic Name Bupropion Hydrochloride
Medication Class Aminoketone Antidepressant
Primary Use Major Depressive Disorder (MDD)
Additional Benefit Smoking Cessation, Seasonal Affective Disorder
Available Form Extended-Release Tablets (SR, XL)
Method of Administration Oral
Frequency Once or twice daily (depending on formulation)
Storage Instructions Store at room temperature (68-77°F), away from moisture and heat
Pregnancy and Breastfeeding Consult healthcare provider; may pass into breast milk
Drug Interactions MAO inhibitors, other antidepressants, certain seizure medications
Manufacturer Multiple manufacturers including Bausch Health Canada Inc.

Buying Bupropion From Canada

Buy Canadian Insulin helps patients access bupropion through participating pharmacy partners.

Pricing may vary depending on product strength, quantity selected, supplier availability, and participating pharmacy partner pricing policies.

Some patients may find pricing through participating pharmacy partners that differs from certain U.S. retail pharmacy prices.

Available services may include:

  • Pricing options based on quantity selected
  • Prescription processing through participating pharmacy partners
  • Shipping options available across eligible U.S. delivery locations
  • Ordering support through phone, email, or live chat
  • Multiple quantity options depending on prescription authorization and supplier availability

Bupropion is a prescription medication that requires review and approval by a licensed healthcare professional and pharmacist before dispensing, where applicable.

Shipping timelines may vary depending on prescription review requirements, inventory availability, destination location, and carrier services.

Prescription Requirement

A valid prescription from a licensed healthcare provider is required before bupropion can be dispensed.

Patients may submit their prescription during checkout or send it separately using one of the approved prescription submission methods.

Prescription Medications Discounts and Coupons

Eligible first-time customers may use coupon code FIRST10 during checkout for qualifying orders, subject to current promotional terms and conditions.

Ordering Information

Have a prescription?

Patients may explore available bupropion prescription options through participating pharmacy partners.

Available ordering features may include:

  • Pricing options based on quantity selected
  • Multiple quantity options depending on prescription details
  • Shipping options with tracking availability when provided by the carrier
  • Customer support assistance through phone, email, or live chat
  • Online and phone ordering availability

Pharmacist Consultation Availability

Licensed pharmacists are available to answer questions regarding bupropion, including dosage instructions, storage recommendations, possible side effects, and medication interactions.

Patients should consult their healthcare provider or pharmacist before starting, stopping, or changing treatment.

Important Treatment Information

Bupropion may be prescribed for major depressive disorder, seasonal affective disorder, or smoking cessation depending on the formulation and your healthcare provider’s recommendations.

Patients should take bupropion exactly as prescribed and attend recommended follow-up appointments.

Mood changes, worsening depression, suicidal thoughts, unusual behavior changes, or other concerning symptoms should be reported to a healthcare provider immediately.

Bupropion should not be stopped abruptly unless directed by a healthcare provider.

What Are the Benefits of Bupropion?

  • Effectively treats major depressive disorder by balancing dopamine and norepinephrine levels
  • Helps manage seasonal affective disorder symptoms during fall and winter months
  • Aids smoking cessation by reducing nicotine cravings and withdrawal symptoms
  • May cause less sexual dysfunction compared to SSRI antidepressants
  • Lower risk of weight gain than many other antidepressant medications
  • Can improve focus and concentration in some patients
  • Available in extended-release formulations for convenient once-daily dosing

Dosage

Bupropion dosage varies based on the condition being treated and the specific formulation prescribed. Your healthcare provider determines the appropriate starting dose and may adjust it based on your response to treatment. Always follow your doctor’s specific dosing instructions rather than self-adjusting your medication.

Dosage Chart

Population / Condition Dosage Recommendation Frequency Route of Administration Notes
Depression (SR) 150mg Starting dose Once daily (morning) Oral May increase after 3-4 days
Depression (SR) 150mg Maintenance Twice daily Oral Doses 8+ hours apart
Depression (XL) 150mg Starting dose Once daily (morning) Oral May increase after 4 days
Depression (XL) 300mg Target dose Once daily (morning) Oral Maximum 450mg daily
Smoking Cessation 150mg Starting dose Once daily Oral Begin 1-2 weeks before quit date
Smoking Cessation 150mg Maintenance Twice daily Oral Continue 7-12 weeks
Elderly Patients 100-150mg Starting dose Once daily Oral Lower doses recommended
Hepatic Impairment Reduced dose As directed Once daily Oral Consult healthcare provider

What Dosage Strengths Does Bupropion Come In?

  • Bupropion SR (Sustained-Release): 100mg, 150mg, 200mg tablets
  • Bupropion XL (Extended-Release): 150mg, 300mg tablets
  • Immediate-Release: 75mg, 100mg tablets (less commonly prescribed)

The SR formulation releases medication over 12 hours and requires twice-daily dosing. XL formulations release medication over 24 hours for once-daily convenience. Your doctor selects the appropriate strength and formulation based on your treatment needs.

Missed Dose

If you miss a Bupropion dose, take it as soon as you remember unless it’s close to your next scheduled dose. Don’t take two doses at once to make up for a missed dose. For SR formulations taken twice daily, skip the missed dose if it’s within 4 hours of your next dose. For XL once-daily formulations, skip the missed dose if it’s late afternoon or evening, as taking it late may interfere with sleep.

Overdose

Bupropion overdose requires immediate medical attention. Call 911 or your local poison control center if you suspect an overdose. Symptoms may include seizures, hallucinations, loss of consciousness, rapid heartbeat, or severe confusion. Never exceed prescribed doses, as Bupropion carries an increased seizure risk at higher amounts.

Usage Guide

  • Swallow tablets whole with water-never crush, chew, or break extended-release formulations
  • Take Bupropion in the morning to minimize sleep disturbances
  • If taking SR twice daily, space doses at least 8 hours apart
  • Take with or without food, but maintain consistency with your routine
  • Avoid taking doses late in the day, which may cause insomnia
  • Don’t stop taking Bupropion suddenly without consulting your doctor
  • Continue taking as prescribed even if you feel better
  • Store tablets at room temperature away from moisture and heat
  • Keep medication in original packaging until ready to use
  • Set daily reminders to maintain consistent dosing schedule
  • Track your mood changes and side effects to discuss with your healthcare provider
  • Allow 4-6 weeks for full therapeutic effects to develop

Bupropion Side Effects

  • Dry mouth and unpleasant taste
  • Insomnia or sleep disturbances
  • Headache and dizziness
  • Nausea and digestive upset
  • Increased sweating
  • Tremor or shakiness
  • Weight loss or decreased appetite
  • Agitation or anxiety
  • Rapid heartbeat

Most side effects decrease as your body adjusts to the medication. Contact your healthcare provider if side effects persist or worsen.

Warnings & Contraindications

  • Do not use if you have a seizure disorder or history of seizures
  • Contraindicated with current or recent MAO inhibitor use (within 14 days)
  • Avoid if you have an eating disorder like anorexia or bulimia
  • Not recommended for patients with abrupt alcohol or sedative withdrawal
  • May increase suicidal thoughts in young adults under 25, especially early in treatment
  • Use cautiously with bipolar disorder-may trigger manic episodes
  • Not suitable for patients with severe hepatic cirrhosis
  • Inform your doctor about head trauma or brain tumor history
  • Disclose all medications and supplements to avoid dangerous interactions
  • Monitor for allergic reactions like rash, itching, or swelling
  • May worsen angle-closure glaucoma
  • Use caution when driving until you know how Bupropion affects you

Drug Interactions

Bupropion interacts with numerous medications, potentially causing serious complications. Always inform your healthcare provider about all prescription drugs, over-the-counter medications, and supplements you take.

Major Interactions:

  • MAO inhibitors (phenelzine, tranylcypromine)-wait 14 days between medications
  • Other antidepressants (SSRIs, SNRIs, tricyclics)
  • Antipsychotic medications
  • Beta-blockers and heart rhythm medications
  • Corticosteroids
  • Medications that lower seizure threshold
  • Tamoxifen and certain cancer treatments
  • CYP2D6 substrates (codeine, tramadol, metoprolol)

Alcohol consumption with Bupropion increases seizure risk. Discuss your alcohol use honestly with your healthcare provider before starting treatment.

Storage Information

  • Store at room temperature between 68-77°F (20-25°C)
  • Keep in original container to protect from light and moisture
  • Store in a dry location-avoid bathrooms where humidity fluctuates
  • Keep out of reach of children and pets
  • Don’t store in vehicles where temperature extremes occur
  • Dispose of expired or unused medication properly through take-back programs
  • Never flush medications down the toilet unless specifically instructed

Alternative Medications

  • SSRIs: Sertraline (Zoloft), Fluoxetine (Prozac), Escitalopram (Lexapro), Paroxetine (Paxil)
  • SNRIs: Venlafaxine (Effexor), Duloxetine (Cymbalta), Levomilnacipran (Fetzima)
  • Other Atypical Antidepressants: Mirtazapine (Remeron), Trazodone
  • Tricyclic Antidepressants: Amitriptyline, Nortriptyline
  • For Smoking Cessation: Varenicline (Chantix), Nicotine replacement therapy

Coupons

Use code FIRST10 at checkout and get 10% off your first Bupropion order.

Savings on Bulk Purchases

Patients can maximize their savings by purchasing Bupropion in larger quantities. The following pricing options are available:

Bupropion SR 150mg

Dosage Quantity Our Price (Canada) Average USA Price
150mg SR 60 tablets $45.00 $120.00
150mg SR 90 tablets $62.00 $180.00
150mg SR 180 tablets $110.00 $360.00

Bupropion XL 150mg

Dosage Quantity Our Price (Canada) Average USA Price
150mg XL 30 tablets $38.00 $95.00
150mg XL 90 tablets $98.00 $285.00

Bupropion XL 300mg

Dosage Quantity Our Price (Canada) Average USA Price
300mg XL 30 tablets $52.00 $140.00
300mg XL 90 tablets $142.00 $420.00

Customer Support & Business Information

For questions regarding prescription processing, product availability, shipping timelines, or account support, contact Buy Canadian Insulin customer support:

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

Customer Support Hours:

Monday-Friday: 7am – 10pm CST

Saturday & Sunday: 9am – 5pm CST

Business Address:

Buy Canadian Insulin

1026 Manitoba Avenue, Suite 1001

Selkirk, MB R1A 4M2

Canada

About Buy Canadian Insulin Services

Buy Canadian Insulin works with participating pharmacy partners to help patients access prescription medications and related healthcare products.

Product availability, pricing, and shipping timelines may vary depending on supplier inventory, participating pharmacy partner availability, and destination location.

Some prescription orders may be fulfilled through licensed pharmacy partners located in Canada or other international fulfillment locations depending on product availability.

Orders are packaged according to pharmacy handling and shipping procedures.

How to Order?

Step 1: Search for Bupropion on our website, select the correct strength and formulation (SR or XL), choose your quantity, then add it to your cart.

Step 2: Enter your contact information, shipping address, and payment details. Create an account if you’re a new customer, or log in if you already have one with us.

Step 3: Upload your prescription directly through the website, email it to info@buycanadianinsulin.com, or fax it to 1-888-234-1275. Our pharmacists verify all prescriptions before processing orders.

Use FIRST10 to claim your 10% discount on your first order.

Have a prescription?

Order Buproprion online today and enjoy a host of benefits, including:

  • Cost Savings: Buy Buproprion at significantly lower prices than in the US prices
  • Bulk Order Discounts: Save more on bulk orders of Buproprion (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped right to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-525-1815
  • SAVE 10% on first order with coupon code: FIRST10

Frequently Asked Questions

No, Bupropion is not an SSRI (selective serotonin reuptake inhibitor). It’s classified as an atypical antidepressant or aminoketone. Unlike SSRIs that primarily affect serotonin, Bupropion works by inhibiting the reuptake of dopamine and norepinephrine, making it chemically and functionally different from medications like Prozac or Zoloft.

Bupropion typically doesn’t cause weight gain and may actually lead to modest weight loss in some patients.

No, Bupropion is not classified as a controlled substance by the DEA. While it affects brain chemistry, it doesn’t produce the euphoric effects or addiction potential associated with controlled substances.

Bupropion can lead to weight loss in some patients, typically ranging from 5-10 pounds over several months. This effect occurs because Bupropion may reduce appetite and increase energy expenditure.

Bupropion typically takes 4-6 weeks to reach full therapeutic effect for depression. Some patients notice initial improvements in energy and concentration within 1-2 weeks, but mood elevation often requires longer.

Bupropion has a half-life of approximately 21 hours, meaning it takes about 5 days for the medication to be completely eliminated from your system after your last dose. However, the active metabolites of Bupropion remain in your body longer, potentially up to 2 weeks. This extended presence is why you should wait before starting certain other medications.

Bupropion is not classified as a stimulant, but it has stimulant-like properties due to its effects on dopamine and norepinephrine. Patients often report increased energy and alertness, which can feel similar to stimulant effects. This is why Bupropion is sometimes prescribed off-label for ADHD, though it’s not FDA-approved for this use.

Yes, Wellbutrin is the brand name for Bupropion. The medication is available as both brand-name Wellbutrin (in SR and XL formulations) and generic bupropion. Both contain the same active ingredient and work identically. Generic bupropion costs significantly less than brand-name Wellbutrin while providing equivalent therapeutic benefits.

Bupropion is not considered addictive in the traditional sense and doesn’t produce the euphoria associated with drugs of abuse. However, stopping Bupropion suddenly can cause withdrawal symptoms like irritability, mood changes, and flu-like symptoms. Always taper off Bupropion gradually under medical supervision rather than stopping abruptly.

You can continue smoking when you first start Bupropion for smoking cessation. Doctors typically recommend beginning the medication 1-2 weeks before your planned quit date. Smoking while taking Bupropion doesn’t cause dangerous interactions, but the medication works best when you eventually stop smoking.

Taking Bupropion at night is generally not recommended because its stimulating effects can interfere with sleep. Most doctors prescribe morning doses for once-daily XL formulations. If taking SR twice daily, the second dose should be in early afternoon, at least 8 hours after the morning dose but early enough to avoid sleep disruption.

Alcohol consumption while taking Bupropion significantly increases seizure risk and should be avoided or minimized. If you drink alcohol, discuss your consumption honestly with your healthcare provider. They may advise abstaining completely or limiting intake to occasional, moderate amounts. Never binge drink while taking Bupropion-this dramatically elevates seizure risk.

Bupropion is classified as FDA Pregnancy Category C, meaning risk cannot be ruled out. Limited human studies exist, but animal studies show potential risks. If you’re pregnant or planning pregnancy, discuss the risks and benefits with your healthcare provider. They’ll weigh the importance of treating your depression against potential fetal risks. Never stop Bupropion suddenly if you become pregnant-consult your doctor first.

Weaning off Bupropion should happen gradually under medical supervision. Your doctor typically reduces your dose by 50-100mg every 1-2 weeks, depending on your current dosage and how long you’ve been taking the medication. This gradual tapering minimizes withdrawal symptoms like mood changes, irritability, and flu-like symptoms. Never stop Bupropion abruptly-sudden discontinuation can cause uncomfortable withdrawal effects and depression relapse.

Disclaimer

Buy Canadian Insulin shares medical information to support your understanding of medications and related health conditions. This content is intended for educational purposes only and should not be considered a substitute for professional medical advice. Always consult with your doctor or pharmacist before beginning or adjusting any prescription. Our trusted pharmacy partners adhere to the strict safety standards established by their respective health authorities to ensure you receive safe medications.

Price Match Guarantee

Price Match Guarantee

We’re dedicated to offering you the best value on every medication. If you discover a lower price on the same product at another verified Canadian online pharmacy, we’ll match it—so you can shop with confidence knowing you’re always getting a fair deal.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online provider with a verifiable address.
  • The competitor’s price must be active and current (not from past or upcoming promotions).
  • The product must match exactly in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be made before completing your order—we cannot adjust prices after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone before checkout.

Note: Price matching does not currently apply to Mounjaro®, Ozempic®, or Saxenda®. This policy may be revised in the future.