Contrave (Bupropion)
from$329.99
$835
Contrave Bupropion Hydrochloride, Naltrexone Hydrochloride
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Ships within 4-10 Business Days
Product of Canada
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from$49.99
$85
Bupropion SR Bupropion HCl
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Bupropion XL (Generic) Bupropion Hydrochloride XL
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Prescription Required
Ships within 4-10 Business Days
Product of Canada

What is Contrave?

Contrave is a prescription weight management medication combining two active ingredients. It contains naltrexone, an opioid antagonist, and bupropion, an antidepressant. Together, these ingredients affect areas of the brain involved in appetite and food cravings. The medication is FDA-approved for chronic weight management in specific adult populations.

Fact Category Fact Details
Generic Name Naltrexone HCl/Bupropion HCl
Medication Class Weight Management Agent
Primary Use Chronic weight management in adults with obesity or overweight with weight-related conditions
Additional Benefit May help reduce food cravings and appetite
Available Form Extended-release tablet (8 mg naltrexone/90 mg bupropion)
Method of Administration Oral
Frequency Twice daily (morning and evening) at maintenance dose
Storage Instructions Store at room temperature between 68°F-77°F (20°C-25°C)
Pregnancy and Breastfeeding Not recommended; both ingredients pass into breast milk
Drug Interactions Interacts with MAOIs, opioids, SSRIs, and many other medications
Manufacturer Currax Pharmaceuticals LLC

Buying Contrave From Canada

Buy Canadian Insulin helps patients access Contrave through participating pharmacy partners.

Pricing may vary depending on product strength, quantity selected, supplier availability, and participating pharmacy partner pricing policies.

Some patients may find pricing through participating pharmacy partners that differs from certain U.S. retail pharmacy prices.

Available services may include:

  • Pricing options based on quantity selected
  • Prescription processing through participating pharmacy partners
  • Shipping options available across eligible U.S. delivery locations
  • Ordering support through phone, email, or live chat
  • Multiple quantity options depending on prescription authorization and supplier availability

Contrave is a prescription medication that requires review and approval by a licensed healthcare professional and pharmacist before dispensing, where applicable.

Shipping timelines may vary depending on prescription review requirements, inventory availability, destination location, customs review, and carrier services.

Prescription Requirement

A valid prescription from a licensed healthcare provider is required before Contrave can be dispensed.

Patients may submit their prescription during checkout or send it separately using one of the approved prescription submission methods.

Prescription Medications Discounts and Coupons

Eligible first-time customers may use coupon code FIRST10 during checkout for qualifying orders, subject to current promotional terms and conditions.

Ordering Information

Have a prescription?

Patients may explore available Contrave prescription options through participating pharmacy partners.

Available ordering features may include:

  • Pricing options based on quantity selected
  • Multiple quantity options depending on prescription details
  • Shipping options with tracking availability when provided by the carrier
  • Customer support assistance through phone, email, or live chat
  • Online and phone ordering availability

Pharmacist Consultation Availability

Licensed pharmacists are available to answer questions regarding Contrave, including dosage instructions, storage recommendations, possible side effects, and medication interactions.

Patients should consult their healthcare provider or pharmacist before starting, stopping, or changing treatment.

Important Treatment Information

Contrave should be used as part of a comprehensive weight management plan that may include dietary changes, physical activity, and ongoing medical supervision.

Patients should follow their healthcare provider’s instructions carefully and attend recommended follow-up appointments.

Mood changes, worsening depression, suicidal thoughts, unusual behavior changes, seizures, or other concerning symptoms should be reported to a healthcare provider immediately.

What Are the Benefits of Contrave?

  • Reduces appetite and food cravings
  • Works on brain areas controlling hunger and reward
  • Approved for long-term weight management
  • Can be used with diet and exercise programs
  • May help with weight-related health conditions
  • Available in convenient oral tablet form

Dosage

Contrave requires gradual dose escalation over four weeks. Start with one tablet daily in the morning. Increase slowly to minimize side effects and improve tolerance. The maintenance dose is two tablets twice daily.

Always follow your healthcare provider’s specific instructions. Individual dosing may vary based on response and tolerability. Never exceed the maximum daily dose of four tablets. Consult your doctor for personalized dosage recommendations.

Dosage Chart

Population/Condition Dosage Recommendation Frequency Route of Administration Notes
Adults (Week 1) 8 mg/90 mg Starting dose Once daily (morning) Oral Take with or without food
Adults (Week 2) 8 mg/90 mg Escalation dose Twice daily (morning and evening) Oral One tablet each time
Adults (Week 3) 8 mg/90 mg Escalation dose Twice daily (morning: 2 tablets, evening: 1 tablet) Oral Total of 3 tablets daily
Adults (Week 4+) 8 mg/90 mg Maintenance dose Twice daily (2 tablets each time) Oral Maximum 4 tablets per day
Hepatic Impairment Reduced dose Consult physician Varies Oral Dose adjustment required
Renal Impairment Reduced dose Consult physician Varies Oral Dose adjustment required
Elderly Patients Standard or reduced Consult physician Varies Oral Monitor closely for side effects

What Dosage Strengths Does Contrave Come In?

  • Extended-release tablet: 8 mg naltrexone HCl/90 mg bupropion HCl
  • Available in bottles of 120 tablets
  • Film-coated for easier swallowing
  • Blue-colored tablets
  • Do not split, crush, or chew tablets

Missed Dose

Take the missed dose as soon as you remember. Skip it if your next scheduled dose is approaching. Never double up to make up for missed doses. Continue with your regular dosing schedule.

Do not exceed four tablets within 24 hours. Contact your healthcare provider if you miss multiple doses. They may adjust your dosing schedule accordingly.

Overdose

Contact Poison Control immediately if overdose occurs. Call emergency services if breathing difficulties develop. Overdose symptoms include seizures, irregular heartbeat, and hallucinations. Loss of consciousness requires immediate medical attention.

Usage Guide

  • Swallow tablets whole with water
  • Do not crush, chew, or split tablets
  • Take morning dose upon waking
  • Take evening dose at least 8 hours after morning dose
  • Can take with or without food
  • Avoid high-fat meals which increase seizure risk
  • Take at same times each day for consistency
  • Do not exceed four tablets in 24 hours
  • Continue taking as prescribed even if feeling well
  • Store remaining tablets at room temperature
  • Keep medication in original container
  • Protect from moisture and light
  • Keep out of reach of children and pets

Side Effects

Common Side Effects

  • Nausea (most common, usually improves with time)
  • Constipation
  • Headache
  • Vomiting
  • Dizziness
  • Insomnia or sleep disturbances
  • Dry mouth
  • Diarrhea

Serious Side Effects

Seek immediate medical attention if you experience:

  • Seizures
  • Severe allergic reactions such as rash, swelling, or trouble breathing
  • Suicidal thoughts or unusual mood changes
  • Severe increases in blood pressure
  • Chest pain
  • Severe dizziness or fainting
  • Eye pain or sudden vision changes
  • Symptoms of liver problems such as yellowing of the skin or eyes

Warnings & Contraindications

  • Do not use if taking MAOIs or within 14 days of stopping MAOIs
  • Contraindicated in uncontrolled hypertension
  • Not for use with seizure disorders or history of seizures
  • Avoid if you have eating disorders like bulimia or anorexia
  • Do not use during opioid withdrawal or with current opioid use
  • Contraindicated in pregnancy and breastfeeding
  • Not recommended for patients under 18 years old
  • Avoid with acute alcohol or sedative withdrawal
  • Do not use with other bupropion-containing products
  • Contraindicated in patients with hepatic impairment
  • May increase suicidal thoughts in some patients
  • Monitor blood pressure regularly during treatment
  • Can trigger manic episodes in bipolar disorder
  • May worsen glaucoma symptoms
  • Use caution when operating machinery until effects are known

Drug Interactions

Contrave interacts with numerous medications. MAOIs cause dangerous interactions and must be avoided. Opioid medications have reduced effectiveness with Contrave. SSRIs and SNRIs increase serotonin toxicity risk.

Medications affecting seizure threshold require careful monitoring. CYP2B6 inhibitors and inducers alter Contrave metabolism. Digoxin levels may increase when taken with Contrave. Antipsychotic medications interact with bupropion component.

Discuss all medications with your healthcare provider. This includes prescription drugs, over-the-counter products, and supplements. Your doctor will evaluate potential interactions. Dose adjustments may be necessary for safety.

Storage Information

  • Store at room temperature (68°F-77°F or 20°C-25°C)
  • Keep in original container with lid tightly closed
  • Protect from moisture and excessive heat
  • Do not store in bathroom or near water
  • Keep away from direct sunlight
  • Store out of reach of children and pets
  • Do not use past expiration date
  • Dispose of expired medication properly through take-back programs

Alternative Medications

  • Phentermine (Adipex-P, Lomaira) – appetite suppressant
  • Orlistat (Alli) – fat absorption blocker
  • Semaglutide (Wegovy, Ozempic) – GLP-1 receptor agonist
  • Liraglutide (Saxenda) – GLP-1 receptor agonist
  • Tirzepatide (Zepbound, Mounjaro) – dual GIP/GLP-1 receptor agonist
  • Phentermine/Topiramate (Qsymia) – combination appetite suppressant

Coupons

Use code FIRST10 at checkout and get 10% off your first Contrave order.

Savings on Bulk Purchases

Patients can explore quantity-based pricing options by purchasing Contrave in larger quantities. The following pricing options are available:

Contrave 8mg/90mg Extended-Release Tablets

Dosage Quantity Our Price (Canada) Average USA Price
8mg/90mg 120 tablets $329.99 $835.00
8mg/90mg 240 tablets $619.98 $1,670.00
8mg/90mg 360 tablets $879.97 $2,505.00

Naltrexone/Bupropion combination products 8mg/90mg

Dosage Quantity Our Price (Canada) Average USA Price
8mg/90mg 120 tablets $49.99 $85.00
8mg/90mg 240 tablets $94.98 $170.00
8mg/90mg 360 tablets $134.97 $255.00

Customer Support & Business Information

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

Customer Support Hours:

Monday-Friday: 7am – 10pm CST

Saturday & Sunday: 9am – 5pm CST

Business Address:

Buy Canadian Insulin

1026 Manitoba Avenue, Suite 1001

Selkirk, MB R1A 4M2

Canada

How to Order?

Step 1: Search for Contrave on our website. Choose the correct strength and quantity you need. Add the medication to your shopping cart.

Step 2: Enter your contact information and shipping address. Provide your payment details securely. Create an account if you’re a new customer. Existing customers can log in to their account.

Step 3: Upload your prescription directly to the site. You can also email it to our team. Fax transmission is another option available. Over-the-counter items don’t require prescriptions.

Use FIRST10 to claim your 10% discount on your first order.

About Buy Canadian Insulin Services

Buy Canadian Insulin works with participating pharmacy partners to help patients access prescription medications and related healthcare products.

Product availability, pricing, and shipping timelines may vary depending on supplier inventory, participating pharmacy partner availability, and destination location.

Some prescription orders may be fulfilled through licensed pharmacy partners located in Canada or other international fulfillment locations depending on product availability.

Orders are packaged according to pharmacy handling and shipping procedures.

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Have a prescription?

Order Contrave online today and enjoy a host of benefits, including:
  • Cost Savings: Buy Contrave at pricing that may be lower than some U.S. retail prices than in the US prices
  • Bulk Order Discounts: Save more on bulk orders of Contrave (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped right to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-525-1815
  • SAVE 10% on first order with coupon code: FIRST10

Frequently Asked Questions

Contrave is a prescription weight management medication. It combines naltrexone and bupropion in one tablet. The medication works on brain areas controlling appetite. It’s approved for chronic weight management in adults.

Clinical studies show Contrave helps with weight loss. Patients typically lose more weight than with diet alone. Results vary based on individual factors. The medication works best with lifestyle changes.

No, Contrave is not classified as a controlled substance. It contains naltrexone and bupropion, neither of which are controlled. The medication has a different mechanism than stimulant weight loss drugs. It’s available only by prescription.

Contrave costs significantly less when ordered from Canada. U.S. prices average around $835 for a month’s supply. Canadian prices through Buy Canadian Insulin start at $329.99. Generic versions cost even less at $49.99.

Many insurance plans cover Contrave with prior authorization. Coverage varies significantly between insurance providers. Some plans require step therapy with other medications first. Check with your insurance company for specific coverage details.

Most patients notice appetite changes within the first few weeks. Significant weight loss typically occurs after 12 weeks of treatment. Maximum benefits may take several months to achieve. Individual response times vary based on multiple factors.

Each Contrave tablet contains 8 mg of naltrexone hydrochloride. The maintenance dose provides 32 mg of naltrexone daily. This amount works synergistically with the bupropion component. The specific ratio is optimized for weight management.

Many side effects diminish after the first few weeks. Nausea typically improves as your body adjusts. Gradual dose escalation helps minimize side effects. Some effects may persist throughout treatment.

Naltrexone has an elimination half-life of about 4 hours. Bupropion’s half-life ranges from 12 to 30 hours. Complete elimination takes several days after stopping. Metabolites may remain slightly longer in the body.

Contrave is FDA-approved for weight management when used appropriately. Like all medications, it carries potential risks. Your doctor evaluates your individual risk factors. Regular monitoring ensures safe use throughout treatment.

Contrave can be taken with or without food. Avoid high-fat meals which increase seizure risk. Taking with food may reduce nausea. Consistency in timing matters more than food intake.

Contrave has demonstrated effectiveness in weight loss through several clinical trials. In the COR-I study, participants taking Contrave lost an average of 5.4% of their body weight over 56 weeks. Additionally, 42% of Contrave users achieved at least a 5% weight loss.

Combining these medications requires careful medical supervision. Your doctor must evaluate potential interactions and risks. Some patients may benefit from combination therapy. Never combine medications without professional guidance.

Disclaimer

Buy Canadian Insulin provides educational information about medications and health conditions for informational purposes only. This content is not intended to replace professional medical advice, diagnosis, or treatment. Prescription medications require a valid prescription review and processing through participating pharmacy partners. Product availability, pricing, and shipping timelines may vary. Consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

Price Match Guarantee

Price Match Guarantee

We’re dedicated to offering you the best value on every medication. If you discover a lower price on the same product at another verified Canadian online pharmacy, we’ll match it—so you can shop with confidence knowing you’re always getting a fair deal.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online provider with a verifiable address.
  • The competitor’s price must be active and current (not from past or upcoming promotions).
  • The product must match exactly in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be made before completing your order—we cannot adjust prices after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone before checkout.

Note: Price matching does not currently apply to Mounjaro®, Ozempic®, or Saxenda®. This policy may be revised in the future.
Kenneth Fill, PharmD, MBA

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.