Crestor (Rosuvastatin)
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Crestor Rosuvastatin Calcium
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Rosuvastatin Calcium (Generic) Rosuvastatin Calcium
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What is Crestor (Rosuvastatin)?

Crestor (rosuvastatin) is a statin medication, otherwise known as an HMG-CoA reductase inhibitor, used to lower cholesterol levels and manage hereditary cholesterol disorders. It is prescribed alongside lifestyle modifications, including exercise and diet, to reduce their levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”) and increase their levels of high-density lipoprotein (LDL cholesterol (“good cholesterol”).

How is Crestor Used?

This medication should be used alongside changes in a patient’s diet and exercise routine to reduce unhealthy cholesterol levels within the body. Most patients will take this medicine once per day and adjust the dose based on individual response and cholesterol levels, as determined by their doctor.

Storage

This medication should be stored at room temperature within the range of 68°F (20°C) to 77°F (25°C), and it should be kept away from direct heat or moisture.

Keep this medication out of the reach of children at all times.

Uses

Crestor is prescribed for a variety of conditions, including but not limited to:

  • hyperlipidemia (high cholesterol levels)
  • atherosclerosis
  • heterozygous familial hypercholesterolemia
  • homozygous familial hypercholesterolemia
  • type III hyperlipoproteinemia (elevated beta-VLDL + intermediate-density lipoprotein, IDL)
  • hypertriglyceridemia
  • the reduction of heart attack and stroke risk

How Does Crestor Work?

This medication functions by inhibiting HMG-CoA reductase, an enzyme responsible for the production of cholesterol within the body. As a consequence, it reduces the unhealthy cholesterol levels within a patient’s body and lowers their risk of cardiovascular events. This medication works best alongside changes to a patient’s diet as well as exercise habits.

Dosage

This medication is available in tablet form in the following strengths:

  • 5 mg
  • 10 mg
  • 20 mg
  • 40 mg

The required dosage for treatment will vary amongst patients and may range between 5 mg and 40 mg once per day. The usual starting dose of Crestor for most adults is 10 mg, taken once per day.

Pediatric patients between the ages of 10 years and 17 years old who require treatment with this medication will typically begin with a once-daily dose of 5 mg, increasing to a once-daily dose of 10 mg if needed.

Those with impaired renal function should begin treatment with a once-daily dose of 5 mg. These individuals should not exceed a maximum dose of 10 mg per day.

Patients who have severe kidney impairment or are of Asian descent should begin treatment with an initial once-daily dose of 5 mg. This is also the appropriate dosage for those who are at risk of developing muscle-related issues when using this medication.

This medication should be taken exactly as instructed by the patient’s prescribing physician.

Overdose

If an overdose of this medication has occurred, the patient’s physician should be informed, or the local Poison Control Center should be contacted as soon as possible. If the individual who has overdosed experiences a severe reaction and stops breathing or loses consciousness, emergency medical care should be sought immediately.

Side Effects

The most common side effects of taking Crestor are as follows:

  • constipation
  • decreased libido or sexual dysfunction
  • feeling dizzy
  • having nightmares
  • headaches
  • nausea
  • sleeping difficulties
  • stomach pain

Please inform your prescribing physician if any of those symptoms become problematic or severe.

Some of the following side effects may occur and should be reported to your doctor immediately:

  • confusion
  • persistent cough
  • enlargement of the breasts
  • hives
  • itchy skin
  • memory trouble
  • pain, tingling, numbness, or weakness in the feet or hands
  • rash on the skin
  • symptoms of damage to the liver
    • abdominal pain
    • appetite loss
    • clay-colored stools
    • dark-colored urine
    • itching
    • jaundice
    • nausea
    • vomiting
  • symptoms of hyperglycemia (high blood glucose levels)
    • excessive appetite
    • frequent urination
    • fruity odor to the breath
    • increased thirst
    • poor wound healing
    • weight loss without a clear explanation
  • symptoms of muscle damage
    • discolored or brown urine
    • fever
    • malaise
    • muscle weakness, tenderness, or pain
  • weakness

Please seek out emergency medical attention if you experience any of the following serious side effects when using this medication:

  • allergic reaction symptoms (severe)
    • breathing difficulties
    • hives
    • swelling of the throat or face
  • breathing difficulties
  • pancreatitis symptoms
    • abdominal swelling
    • upper abdominal pain on the left side
    • chills
    • fever
    • nausea
    • pain in the back
    • rapid heart rate
  • skin rash that is severe and includes peeling and blistering
  • trouble swallowing

Warnings & Precautions

Alcohol Consumption

Consuming alcohol in excess or regularly while using this medication increases a patient’s risk of experiencing liver impairment and other hepatic issues. These patients may require additional monitoring during treatment to ensure proper liver function and safety while using Crestor.

Diabetes

This medication is capable of increasing a patient’s blood glucose levels and affecting their overall glucose tolerance. Patients with diabetes may need to monitor their blood glucose levels more closely during treatment with Crestor.

Those who are at risk of developing diabetes or who currently have the condition should be sure to discuss these aspects of their health history with their physician before beginning treatment with this medication, as this may impact the efficacy of the medication as well as dosage requirements.

Geriatric Patients

Senior patients above the age of 65 years will commonly require additional monitoring when using this medication to detect any muscle-related issues that may arise during treatment.

Hepatic Function

This medication is capable of impairing a patient’s liver function, and this may sometimes even result in liver failure. Patients who regularly consume alcohol are at a higher risk of experiencing hepatic impairment. Individuals using Crestor who experience any of the following liver-related symptoms should inform their physician as soon as possible: itchy skin, abdominal swelling, abdominal pain, pale-colored stools, dark-colored urine, jaundice, malaise, fatigue, or loss of appetite.

Those who have higher-than-normal liver function tests or who currently have active liver disease should not use this medication. Those with a history of hepatic impairment or other liver-related conditions should be sure to inform their prescribing physician of these aspects of their medical history before beginning treatment with this medication.

Hypersensitivity

Some patients will experience “hypersensitivity syndrome” when using a “-statin” medication like Crestor. These individuals will experience severe allergic reaction symptoms such as flu-like symptoms, swollen glands, blistering, skin rash, jaundice, or fever. Patients using this medication who experience any of these symptoms should seek out emergency medical attention as quickly as possible.

Muscle Damage

Some “-statin” medications have been linked to muscle damage, especially in patients who are taking higher doses of these medications. As a “statin,” Crestor also comes with this risk. Patients with the following may be more likely to experience muscle damage when using this medication: a family history of muscle-related disorders, the use of additional cholesterol-lowering medications, age above 70 years, being of Asian descent, have had any past muscle-related problems, have thyroid problems, have impaired hepatic or renal function, are taking additional medications for other conditions, have diabetes, consume three or more alcoholic beverages per day, have recently had a tissue injury, or have recently had any type of surgery.

Patients using this medication should report any unusual symptoms to their prescribing physician as soon as possible. This includes issues such as fever, dark-colored or brown urine, cramps, muscle pain, malaise, muscle weakness, or muscles that feel tender.

Renal Function

Individuals with kidney disease or impaired renal function should be sure to inform their doctor of these conditions before beginning treatment with this medication. In some cases, changes in the required dosage and any monitoring requirements may be necessary to ensure that Crestor is both safe and effective in these particular individuals.

Pediatric Patients

This medication may be used in patients ranging from 10 years to 17 years of age who have been diagnosed with certain cholesterol-related disorders that are hereditary. However, any children in this age range who are capable of menstruation should have at least been menstruating for one full year before using Crestor.

It has not been determined if this medication is safe or effective in patients below the age of 10.

Any pediatric patient using Crestor should be closely monitored for the duration of their treatment with this medication.

Pregnancy and Breastfeeding

This medication is not safe for use by pregnant individuals, and any patients using this medication who become pregnant during treatment should inform their prescribing physician immediately.

Additionally, it has not been determined if this medication is safe for use by patients who are breastfeeding. This medication may pass into breast milk and affect a breastfed child. Patients desiring to breastfeed while using Crestor should discuss the possible risks with their physician before continuing to do so.

Additional Factors That May Impact the Safety and Efficacy of Crestor

If any of the following apply, be sure to discuss these factors with your doctor before beginning this medication, as these individuals should not use the 40mg strength of Crestor:

  • alcoholism or excessive alcohol consumption
  • being of Asian descent (Asian-Indian, Korean, Japanese, Filipino, Chinese, or Vietnamese)
  • current use of a fibrate
  • current use of niacin
  • experiencing muscle damage when previously using another “-statin” medication
  • family history of muscle disorders
  • having an inherited muscle disorder
  • having other health conditions that may impact the amount of Crestor within the body
  • hypothyroidism
  • severely impaired renal or hepatic function
  • taking other medications that may impact the amount of Crestor within the body

Drug Interactions

Speak to your doctor about any medications or herbal supplements you are currently taking before beginning treatment with this medication. Discuss any concerns you may have with your doctor or a trusted pharmacist.

The following medications are known to interact with Crestor and may result in decreased efficacy of the medication or an increased risk of adverse side effects:

  • aluminum hydroxide
  • antacids
  • apalutamide
  • atazanavir
  • atorvastatin
  • bezafibrate
  • calcium carbonate
  • carbamazepine
  • clopidogrel
  • cobicistat
  • cyclosporine
  • dronedarone
  • elagolix
  • eltrombopag
  • eslicarbazepine
  • fenofibrate
  • gemfibrozil
  • glecaprevir
  • grazoprevir
  • hepatitis C antivirals
  • HIV protease inhibitors
  • indinavir
  • itraconazole
  • ledipasvir
  • letermovir
  • lovastatin
  • magnesium hydroxide
  • niacin (nicotinic acid)
  • niacinamide
  • pazopanib
  • pibrentasvir
  • raltegravir
  • regorafenib
  • repaglinide
  • rifampin
  • ritonavir
  • saquinavir
  • simvastatin
  • sofosbuvir
  • “-statin” medications (anti-cholesterol medications)
  • teriflunomide
  • tolvaptan
  • trabectedin
  • velpatasvir
  • voxilaprevir
  • warfarin

Alternative Medications

For patients who are unable to take Crestor or experiencing significant adverse side effects, alternative medications may be used to treat some of the associated conditions for which this medication is commonly prescribed:

  • alirocumab (Praluent)
  • atorvastatin (Lipitor)
  • evolocumab (Repatha)
  • ezetimibe (Zetia)
  • pravastatin (Pravachol)
  • simvastatin (FloLipid, Zocor)

Cost & Ordering Information

Buy Crestor Through Buy Canadian Insulin

Buy Canadian Insulin helps patients access Crestor through participating pharmacy partners.

Pricing may vary depending on product strength, quantity selected, supplier availability, and participating pharmacy partner pricing policies.

Some patients may find pricing through participating pharmacy partners that differs from certain U.S. retail pharmacy prices.

Available services may include:

  • Pricing options based on quantity selected
  • Prescription processing through participating pharmacy partners
  • Shipping options available across eligible U.S. delivery locations
  • Ordering support through phone, email, or live chat
  • Multiple quantity options depending on prescription authorization and supplier availability

Crestor is a prescription medication that requires review and approval by a licensed healthcare professional and pharmacist before dispensing, where applicable.

Shipping timelines may vary depending on prescription review requirements, inventory availability, destination location, customs review, and carrier services.

Prescription Medication Discounts and Coupons

Eligible first-time customers may use coupon code FIRST10 during checkout for qualifying orders, subject to current promotional terms and conditions.

Ordering Information

Have a prescription?

Patients may explore available Crestor prescription options through participating pharmacy partners.

Available ordering features may include:

  • Pricing options based on quantity selected
  • Multiple quantity options depending on prescription details
  • Shipping options with tracking availability when provided by the carrier
  • Customer support assistance through phone, email, or live chat
  • Online and phone ordering availability

How to Order Crestor

Step 1

Search for Crestor on the website, select the prescribed strength and quantity, and add it to your cart.

Step 2

Enter your shipping information and payment details. Create an account or log in to continue.

Step 3

Upload your prescription through the secure prescription portal, email it to info@buycanadianinsulin.com, or fax it to 1-888-234-1275.

Pharmacist Consultation Availability

Licensed pharmacists are available to answer questions regarding Crestor, including administration instructions, storage recommendations, possible side effects, and medication interactions.

Patients should consult their healthcare provider or pharmacist before starting, stopping, or changing treatment.

Important Treatment Information

Crestor should be taken exactly as prescribed by a healthcare provider.

Patients should continue following recommended dietary changes, exercise plans, and other lifestyle recommendations while using Crestor.

Do not stop taking Crestor without first speaking with a healthcare provider.

Customer Support & Business Information

For questions regarding prescription processing, product availability, shipping timelines, or account support, contact Buy Canadian Insulin customer support:

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

Customer Support Hours:

Monday-Friday: 7am – 10pm CST

Saturday & Sunday: 9am – 5pm CST

Business Address:

Buy Canadian Insulin

1026 Manitoba Avenue, Suite 1001

Selkirk, MB R1A 4M2

Canada

About Buy Canadian Insulin Services

Buy Canadian Insulin works with participating pharmacy partners to help patients access prescription medications and related healthcare products.

Product availability, pricing, and shipping timelines may vary depending on supplier inventory, participating pharmacy partner availability, and destination location.

Some prescription orders may be fulfilled through licensed pharmacy partners located in Canada or other international fulfillment locations depending on product availability.

Orders are packaged according to pharmacy handling and shipping procedures.

Frequently Asked Questions

Crestor is a “statin” medication that lowers cholesterol levels when dietary changes and exercise are not enough to improve an individual’s LDL and HDL levels.
This medication is considered a “statin” medication.
You should not take Crestor if you are pregnant, breastfeeding, planning to become pregnant, have any hepatic impairment, or are allergic to any of the ingredients included in this medication.
The medication is intended to increase a patient’s HDL cholesterol levels, decrease their LDL cholesterol levels, and slow the buildup of plaque within the patient’s arteries to assist in further lowering and managing their cholesterol levels.
This medication functions by boosting the uptake as well as the breakdown of cholesterol in the blood that takes place within an individual’s liver. It also inhibits the enzyme responsible for cholesterol production in the patient’s liver, preventing any increase in the cholesterol present within the body.
This medication should be taken exactly as instructed by the patient’s prescribing physician. Typically, this medication is taken orally, once per day, and swallowed whole. It may be taken with or without food.
Most patients using this medication see improvement in their cholesterol levels within two to four weeks after beginning treatment with Crestor. However, due to a variety of factors, the results that a patient experiences with this medication may vary.
The most common side effects experienced by patients using this medication include abdominal pain, headaches, muscle pain, muscle aches, nausea, and feelings of weakness. Some individuals have also experienced confusion and memory loss when using this medication.
If you have missed a dose of this medication, you should generally take the missed dose as soon as you remember. However, patients should never take two doses of this medication within the span of 12 hours due to the risk of overdose. If you have ingested too much of this medication, please seek emergency medical attention or contact your doctor as soon as possible.
Patients that are currently pregnant or planning to become pregnant should not use this medication due to the significant risks it poses to an unborn child. Additionally, patients using this medication should not breastfeed due to this medication’s ability to pass through breastmilk and affect a breastfed child.
Individuals using this medication should avoid consuming foods that are high in cholesterol or fat as this counteracts the function of the medication and will make it less effective. Certain antacids that include magnesium or aluminum may impact the absorption and should not be taken within two hours of ingesting Crestor. Patients should avoid alcohol consumption as well, as this can increase the levels of triglycerides within the body and also increase the patient’s risk of developing liver damage.
If an overdose is suspected or has occurred, the individual’s physician or local Poison Control Center should be contacted as soon as possible. If the individual who has ingested too much Crestor experiences a severe reaction and either stops breathing or loses consciousness, emergency medical attention should be sought immediately.
The active ingredient in Crestor is rosuvastatin calcium. The inactive ingredients in this medication include the following: red ferric oxide, yellow ferric oxide, titanium dioxide USP, triacetin, hypromellose, crospovidone, tribasic calcium phosphate, lactose monohydrate, and microcrystalline cellulose.
This medication comes in tablet form and is available in the following strengths: 5 mg, 10 mg, 20 mg, and 40 mg.
This medication is known to interact with the following types of medications: blood thinners, acid-reducing medications, HIV medications, other cholesterol medications, immunosuppression medications, medications for hepatitis C, gout medications, and medications used to treat cancer. Please inform your physician of all current medications you are taking before beginning treatment with this medication.
Patients that are prescribed Crestor should be aware it is associated with a risk of developing myopathy, which can lead to serious health concerns that may eventually become fatal, as well as impaired liver function. Any unexplained or unusual fatigue—especially along with weakness, tenderness, or pain in one’s muscles—should be reported to the patient’s physician as soon as possible.

Disclaimer

Buy Canadian Insulin provides educational information about medications and health conditions for informational purposes only. This content is not intended to replace professional medical advice, diagnosis, or treatment. Prescription medications require valid prescription review and processing through participating pharmacy partners. Product availability, pricing, and shipping timelines may vary. Consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

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We’re dedicated to offering you the best value on every medication. If you discover a lower price on the same product at another verified Canadian online pharmacy, we’ll match it—so you can shop with confidence knowing you’re always getting a fair deal.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online provider with a verifiable address.
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Note: Price matching does not currently apply to Mounjaro®, Ozempic®, or Saxenda®. This policy may be revised in the future.

Kenneth Fill, PharmD, MBA

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.