Humalog Mix 25 KwikPen 100 Units / mL
Humalog Mix 25 KwikPen
Insulin Lispro
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Humalog mixes start working faster than other insulins that contain regular human insulin.

Using Humalog Premixed Insulin KwikPen

Humalog Mix 25 KwikPenHumalog® KwikPen® is a lightweight, small pen that’s prefilled with mealtime insulin. Plus, since it doesn’t need to be refrigerated after first use, you can take anywhere. Due to its small size and portability, you can take it with you. Store it in your backpack, purse or pocket. It’s a good idea to always carry an extra pen.

Once you start using Humalog KwikPen, it should be stored at room temperature, below 86°F (30°C), and must be used within 10 days or be discarded, even if it still contains Humalog.

About Humalog Mix 25 Kwikpen 100IU/ml

The Humalog Mix 25 Kwikpen 100IU/ml is an insulin pen that contains a combination of two medications, insulin lispro (25%) that has a fast onset of action and insulin lispro protamine (75%) that has a prolonged duration of action. Together, these two medicines ensure a consistent and rapid sugar control throughout the day by facilitating re-uptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.

Insulin should be part of your diabetes treatment program advised by a doctor, combined with a healthy diet, exercise and weight reduction.

The Humalog Mix25 KwikPen is normally prescribed alongside a long-acting type of insulin by doctors. It effectively manages blood sugar levels for people with type 1 and type 2 diabetes to avoid diabetes-related complications.

Humalog Mix 25 Kwikpen: Usage

Your doctor or nurse should instruct you on how to properly administer your insulin correctly.

Humalog Mix 25 Kwikpen is injected under the skin (subcutaneously). Inject in the abdomen for faster absorption. Insulin can also be injected in the skin of the upper legs and arms or buttocks. After injection, do not massage the area of injection.

It is taken 15 minutes before your meal or within 20 minutes of starting your meal.

It is important to monitor blood sugar levels regularly and share results with your doctor so they can provide the correct dosage based on your individual needs.

Rotate injection sites in order to prevent hard lumps from forming at injection sites.

Low blood sugar or hypoglycemia may result when taken with other antidiabetic medicines, skipping or delaying meals or consuming alcohol.

Carry a sugar source such as glucose tablets, candy or sugary drink for immediate relief from hypoglycemia.

Open insulin vials or cartridges can be stored at room temperature for up to 4 weeks. Unopened vials should refrigerated at 2°C–8°C.

How to inject insulin?

1. Wash hands before injecting.
2. Choose area for injection
3. Clea area of injection
4. Stabilie the skin by pinching it
5. Insert the needle
6. Press the knob
7. Pull the needle out and apply gentle pressure over site of injection for a few seconds
8. Using the outer needle cap, unscrew needle and dispose as instructed by pharmacist

Preparation of Humalog Mix 25 Kwikpen 100IU/ml

You should rotate the Humalog Mix 25 Kwikpen in the palm of your hand ten times and inverted 180 degrees ten times before use in order to re-suspend the insulin until it appears cloudy or milky. Do not use until the contents are mixed. Do not shake the device too hard as this may cause frothing can can interfere with dose measuring. Examine the device for any particles floating inside giving a frosted appearance.

How to prime your Humalog Mix 25 Kwikpen

Priming your pen is required. If this is not done or done correctly, then you may receive too much or too little insulin. To do, turn the dial 2 units. Hold your pen with needle pointing up. Tap cartridge holder to get air bubbles to the top. Push the dose knob until the dosage window stops at “0”. Hold dose knob and count to five. You should then see the insulin at the tip of the needle.

What to do if the dose knob becomes stiff or hard to push?

Pushing the dose knob on the pen slowly will make it easier to inject. Put on a new needle and prime the pen if the needle is blocked.

Humalog Mix 25 Kwikpen: Side Effects

An essential part of managing your diabetes is through the management of blood glucose levels. If you control your blood sugar levels you can avoid serious complications such as nerve damage, eye damage, kidney damage and loss of limbs.

Managing blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

As with most insulin medications, the most common side effect is low blood sugar levels also known as hypoglycemia. This can be avoided by injecting the correct dosage, having regular meals and monitoring blood sugar levels regularly. Avoid excessive alcohol consumption as this can also lower blood sugar levels.

Allergic reactions at the site of injection such as redness, hard lumps (lypodystrophy), and swelling are also common. Some have reported itching and rashes while taking insulin.

Common side effects of Humalog Mix25:

  • Low blood sugar levels (hypoglycemia). Symptoms of hypoglycemia may include confusion, headache, palpitations, shakiness, increased heartbeat, anxiety, blurred vision, headache, vomiting, sweating, mood changes, hunger, irritability and listlessness.
  • Allergic reaction at injection site
  • Lipodystrophy (skin thickening or pits at injection site)
  • Rash
  • Itching

The following drugs may require an increase of insulin:

  • corticosteroids
  • isoniazid
  • estrogens
  • oral contraceptives
  • certain lipid-lowering drugs (ie niacin)
  • phenothiazines
  • thyroid replacement therapy

The following drugs can decrease insulin requirement:

  • angiotensin-converting-enzyme inhibitors
  • oral antidiabetic agents
  • salicylates
  • angiotensin II receptor blocking agents
  • certain antidepressants (monoamine oxidase inhibitors)
  • beta-adrenergic blockers
  • inhibitors of pancreatic function
  • beta-adrenergic blockers may mask symptoms of hypoglycemia for some.
  • sulfa antibiotics
  • alcohol

Most side effects do not require medical attention and disappear as your body adjusts to the medication.

It is important to advise your doctor if you are experiencing any side effects so they can adjust your dosage and treatment.

Humalog Mix 25 Kwikpen: Warnings & Precautions

Notify your doctor if you currently have any liver, kidney or heart problems before starting treatment.

Let your doctor know if you are pregnant or breastfeeding as the dosage may be adjusted.

Humalog Mix 25 Kwikpen quick pen is generally safe to take during pregnancy. Animal studies have shown that there are little to no side effects to developing babies, however there have been limited human studies. Insulin requirements usually fall during the first trimester and increase during the second and third trimesters. Inform your doctor is you are pregnant.

It is also safe during breastfeeding. Human studies have shown that the medication does not pass through breast milk in a significant amount that would be harmful to the baby. During breastfeeding your doctor may recommend adjusting dosage requirements, diet or both.

Do not stop taking medication unless instructed by your doctor.

Do not drive or operate heavy machinery if blood sugar levels are too high or too low unless suggested differently by your doctor.

Patients with liver or kidney disease should use with caution. Consult your doctor as you may require a dose adjustment.

Frequently Asked Questions

Humalog Mix 25 is a combination of insulin lispro, which is short-acting, and insulin lispro protamine, which is long-acting. This allows Humalog Mix 25 to provide diabetic patients with the benefits of both types of insulin, giving them quick and long-lasting effects compared to the other types of insulin available.

The insulin found in Humalog is solely insulin lispro. This is a short-acting insulin that works quickly and also only lasts a few hours. The combination of insulins found in the Humalog Mix 25 KwikPen includes both short-acting (insulin lispro) as well as long-acting (insulin lispro protamine) insulin. This means that the effects of the insulin provided when using a Humalog Mix 25 KwikPen will begin quickly and also last for a longer period of time compared to Humalog (insulin lispro) by itself.

Each Humalog Mix 25 KwikPen contains active ingredients in a solution of 25% insulin lispro and 75% insulin lispro protamine. The following inactive ingredients are also included: water, zinc oxide, dibasic sodium phosphate 7 H2O, glycerol, phenol (0.8mg/ml), m-cresol (1.76mg/ml), and protamine sulfate. The pH may also be adjusted with the addition of sodium hydroxide or hydrochloric acid.

When using a Humalog Mix 25 KwikPen for the management of your diabetes, your doctor will provide detailed instructions regarding when and how to inject the medication based on your condition. However, most patients will need to use their Humalog Mix 25 KwikPen 15 minutes before having a meal. They will need to inject the medication into the fatty layer of tissue right underneath the skin located on the back of their arms, stomach, or top/outside of the thigh. Food should then be consumed shortly after administering the medication to avoid hypoglycemia occurring. A new needle should be used each time the Humalog Mix 25 KwikPen is used to avoid infection or other issues from arising, and patients should never share their Humalog Mix 25 KwikPen with anyone else.

The combination of two different types of insulins in a Humalog Mix 25 KwikPen means it is both short-acting as well as long-acting. The insulin lispro (25%) is short-acting, and the insulin lispro protamine (75%) is long-acting.

An unopened Humalog Mix 25 KwikPen that is not currently in use should be stored in a refrigerator until it is either used or reaches its expiration date. After opening your Humalog Mix 25 KwikPen, the pen should be stored at room temperature and used within the next ten days. If the medication within the KwikPen looks as if it contains particles or is cloudy, do not use the injection pen. Contact your doctor or pharmacist regarding acquiring a new KwikPen.

The insulin mix in a Humalog Mix 25 KwikPen typically takes about ten to fifteen minutes to begin working after the medication has been injected. Due to it being a mixture of short-acting as well as long-acting insulin, it works quickly after injection and continues to work until about 18 hours have passed.

It is not recommended for patients who use insulin to do so alongside alcohol consumption. Consuming alcohol may impact a diabetic patient’s blood sugar levels and result in hyperglycemia or hypoglycemia, depending on a variety of factors. With such fluctuations taking place, this may result in adverse effects and poor management of the patient’s condition.

The Humalog Mix 25 KwikPen contains a combination of 25% insulin lispro along with 75% insulin lispro protamine. These two serve as a combination of fast-acting and long-acting insulins to more effectively manage blood glucose levels in those with diabetes.