Buy Humalog Mix 50 Cartridge from Canada
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Humalog Mix 50 Cartridge Insulin Lispro
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Cold-Chain Shipping Notice

This medication requires specialized cold-chain packaging to help maintain its quality and integrity during transit. Each shipment includes a temperature indicator to monitor storage conditions throughout the shipping process.

Do NOT use this medication if the attached temperature indicator shows that it was exposed to temperatures below 2°C (36°F) or above 8°C (46°F). If the temperature indicator shows that the acceptable temperature range has been exceeded, or if you have any concerns about the condition of your shipment upon arrival, do not use the medication and contact our pharmacy immediately for further instructions and assistance.

Please inspect your shipment and the temperature indicator as soon as it is delivered.

What is a Humalog Mix 50 Cartridge?

Humalog Mix 50 Cartridges offer a solution for managing diabetes by combining two types of insulin in one convenient cartridge.

This formula consists of 50% insulin lispro, a fast-acting insulin that rapidly lowers blood sugar after meals, and 50% insulin lispro protamine, which provides steady blood sugar control throughout the day.

This dual-action approach ensures both immediate and long-lasting blood sugar management, helping prevent complications associated with diabetes, such as vision problems, kidney damage, and nerve issues.

Designed for ease of use, these cartridges are compatible with insulin pens, allowing for precise dosing and simple administration.

Ingredients in Humalog Mix 50 Cartridges

Humalog Mix 50 Cartridges contain 100 units/mL of human insulin analogue.

The insulin in these cartridges is a blend of 50% insulin lispro injection and 50% insulin lispro protamine suspension.

The inactive ingredients include glycerol, dibasic sodium phosphate, m-cresol, zinc, and water.

Hydrochloric acid or sodium hydroxide may be added to adjust the pH. Additionally, Humalog Mix 50 contains phenol, protamine sulfate, and zinc oxide.

How Does a Humalog Mix 50 Cartridge Work?

Humalog Mix 50 Cartridge works by combining two types of insulin to help manage blood sugar levels in people with diabetes.

The fast-acting insulin lispro in the mix starts working quickly after you take it, helping to lower blood sugar levels right after you eat.

The longer-acting insulin lispro protamine remains effective throughout the day, helping to maintain steady blood sugar control.

Together, they help your body use sugar more effectively by allowing your muscles and fat to absorb glucose and reducing the amount of sugar your liver produces. This combination helps keep your blood sugar levels stable and reduces the risk of diabetes-related complications.

Dosage Information and Usage

Dosage Form and Strengths of Humalog Mix 50 Cartridge

  • Cartridge: 3 mL (contains 50% insulin lispro and 50% insulin lispro protamine)
  • KwikPen: 3 mL prefilled pen

Usage

Prepare Your Pen:

  • Start by washing your hands thoroughly.
  • Gently roll and then invert the pen several times to mix the insulin until it appears white and cloudy.
  • Attach a new needle by removing the paper tab and screwing it onto the pen.

Prime the Pen:

  • Turn the dose knob to select 2 units.
  • Hold the pen with the needle pointing up and tap the cartridge holder to move any air bubbles to the top.
  • Push the dose knob until you see a stream of insulin from the needle, ensuring the pen is ready for accurate dosing.

Select Your Dose:

  • Turn the dose knob to set the number of units you need to inject.
  • Make sure the dose indicator is aligned with your selected dose.

Inject the Insulin:

  • Choose an injection site on your abdomen, thigh, upper arm, or buttocks.
  • Clean the area with an alcohol swab and let it dry.
  • Insert the needle into your skin at the chosen site.
  • Press the dose knob in and hold it for 5-10 seconds to ensure the full dose is delivered.

After the Injection:

  • Carefully remove the needle from your skin.
  • Dispose of the used needle safely in a sharps container.
  • Replace the pen cap to keep it clean and ready for the next use.

Injection site

Humalog Mix 50 should be injected under the skin, usually in the stomach, buttocks, upper legs, or upper arms.

It’s important to rotate your injection sites to avoid skin problems like lumps or thickened areas, which can affect how well the insulin works.

Always use a different spot within the same area to prevent irritation. If you notice any changes in your skin where you inject, talk to your doctor about adjusting your injection routine or monitoring your blood sugar more closely.

Storage Information

Store Humalog Mix50 in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Never freeze it.

If Humalog Mix50 has been frozen, do not use it. If you keep it outside the refrigerator, make sure it stays below 30°C (86°F).

In this case, you need to use it within 28 days, or else it should be thrown away, even if there is still some left in the vial.

Side Effects of Humalog Mix 50 Cartridge

Common Side Effects

  • Low blood sugar (hypoglycemia)
  • Reactions at the injection site
  • Skin thickening or pits at the injection site (lipodystrophy)
  • Weight gain
  • Swelling in hands or feet
  • Itching
  • Rash

Serious but Rare Side Effects

  • Severe allergic reaction (whole body reaction)
  • Low potassium levels in the blood (hypokalemia)
  • Heart failure (especially when taken with certain diabetes pills like thiazolidinediones or “TZDs”)
  • Trouble breathing or shortness of breath
  • Swelling of the face, tongue, or throat
  • Extreme drowsiness, dizziness, or confusion

Many side effects fade as your body gets used to the medication and typically don’t need immediate medical attention. If issues persist, be sure to contact your doctor.

Warnings and Precautions

  • Use with caution in patients with kidney or liver disease: People with kidney or liver problems should be careful when using Humalog Mix 50, as these conditions can affect how the body processes insulin, increasing the risk of low blood sugar (hypoglycemia). Close monitoring by a healthcare provider is essential to ensure safe and effective treatment.
  • Safe for pregnant or breastfeeding women: Humalog Mix 50 is generally considered safe for use during pregnancy and breastfeeding. Studies show it does not pass significantly into breast milk or harm the baby. However, your doctor may adjust your dosage to suit your specific needs during this period.
  • Avoid excessive alcohol consumption: Drinking too much alcohol while using Humalog Mix 50 can lead to dangerously low blood sugar levels (hypoglycemia). It’s important to limit alcohol intake to avoid these complications.
  • Do not share insulin or syringes: Sharing insulin pens or syringes with others can lead to the transmission of serious infections, including blood-borne diseases. Always use your insulin supplies to protect your health.
  • Be aware of the risks of unmanaged diabetes: If diabetes is not properly managed, it can lead to severe complications such as blindness, kidney failure, strokes, poor circulation, and nerve damage. Proper diabetes management can help prevent or reduce these risks.
  • Caution when operating machinery or driving: High or low blood sugar levels can impair your ability to concentrate and react quickly, making activities like driving or operating heavy machinery dangerous. Always ensure your blood sugar levels are stable before engaging in such tasks.
  • Double-check the insulin cartridge before use: Humalog comes in various forms, and it’s easy to confuse one product with another. Always verify that you’re using the correct insulin cartridge before pre-filling your pen to avoid medication errors.

Overdosage of Humalog Mix 50 Cartridge

Overdosing on Humalog Mix 50 can lead to serious conditions such as hypoglycemia (low blood sugar) and hypokalemia (low potassium levels).

Mild hypoglycemia can usually be treated by consuming glucose, but severe cases may require emergency treatment with a glucagon injection or concentrated intravenous glucose.

In such cases, close monitoring and sustained carbohydrate intake may be needed to prevent the recurrence of low blood sugar.

Additionally, hypokalemia should be corrected appropriately to avoid further complications.

Factors that can contribute to an overdose include taking too much insulin, missing meals, excessive physical activity, or interactions with other medications.

Drug Interactions With Other Medications

  • Antidiabetic agents, ACE inhibitors, angiotensin II receptor blockers, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics: These medications can increase the risk of low blood sugar (hypoglycemia). You may need to adjust your Humalog Mix50/50 dose and check your blood sugar levels more often.
  • Atypical antipsychotics (e.g., olanzapine, clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), thyroid hormones: These drugs can reduce the effectiveness of Humalog Mix50/50 in controlling blood sugar. You may need to adjust your insulin dose and monitor your blood glucose levels more frequently.
  • Alcohol, beta-blockers, clonidine, lithium salts: These substances can either enhance or reduce the blood sugar-lowering effects of Humalog Mix50/50. Regular blood glucose monitoring and potential dose adjustments may be necessary.
  • Beta-blockers, clonidine, guanethidine, reserpine: These medications may hide symptoms of low blood sugar, such as shakiness or sweating, making it harder to detect hypoglycemia. Increased blood sugar monitoring is recommended.

Alternative Medications

Cost & Ordering Information

Buy Humalog Mix 50 Cartridge Through Buy Canadian Insulin

Buy Canadian Insulin helps patients access prescription medication options through participating pharmacy partners.

Pricing may vary depending on product strength, quantity selected, supplier availability, and participating pharmacy partner pricing policies.

Some patients may find pricing through participating pharmacy partners that differs from certain U.S. retail pharmacy prices.

Available services may include:

  • Pricing options based on quantity selected
  • Prescription processing through participating pharmacy partners
  • Shipping options available across eligible U.S. delivery locations
  • Ordering support through phone, email, or live chat
  • Multiple quantity options depending on prescription authorization and supplier availability

Humalog Mix 50 Cartridge requires a valid prescription.

Prescription medications require review and approval by a licensed healthcare professional and pharmacist before dispensing, where applicable.

Shipping timelines may vary depending on prescription review requirements, inventory availability, destination location, customs processing, and carrier services.

Pricing Table for Humalog Mix 50 Cartridge

Strength Quantity Price (USD) Price Per Cartridge (USD)
100u/mL 5 cartridges $102.00 $20.40
100u/mL 10 cartridges $202.00 $20.20
100u/mL 15 cartridges $300.00 $20.00
100u/mL 20 cartridges $396.00 $19.80
100u/mL 25 cartridges $485.00 $19.40

Prescription Medication Discounts and Coupons

Eligible first-time customers may use coupon code FIRST10 during checkout for qualifying orders, subject to current promotional terms and conditions.

Ordering Information

Patients with a valid prescription may explore available Humalog Mix 50 Cartridge options through participating pharmacy partners.

Available ordering features may include:

  • Pricing options based on quantity selected
  • Multiple quantity options depending on prescription details
  • Shipping options with tracking availability when provided by the carrier
  • Customer support assistance through phone, email, or live chat
  • Online and phone ordering availability

Prescription submission options may include secure online upload, fax, or customer support assistance.

Refrigerated Shipping Information

Humalog Mix 50 Cartridge is a temperature-sensitive medication.

Special packaging may be used to help maintain recommended storage conditions during transit.

Shipping timelines may vary depending on inventory availability, destination location, weather conditions, customs processing, and carrier services.

Upon delivery, inspect the package and medication. Contact customer support if you have concerns regarding temperature exposure or product condition before use.

Pharmacist Consultation Availability

Pharmacist consultation may be available through participating pharmacy partners. Contact customer support for assistance with prescription-related questions.

Possible Dispensing Countries

Some prescription orders may be fulfilled through licensed pharmacy partners located in Canada or other international fulfillment locations depending on product availability, prescription requirements, and pharmacy partner availability.

Customer Support & Business Information

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

Customer Support Hours:

Monday-Friday: 7am – 10pm CST

Saturday & Sunday: 9am – 5pm CST

Business Address:

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1026 Manitoba Avenue, Suite 1001

Selkirk, MB R1A 4M2

Canada

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  • Cost Savings: Buy Humalog Mix 50 Cartridges at significantly lower prices than in the US prices
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Frequently Asked Questions

Humalog Mix50 is used to help manage blood sugar levels in people with diabetes. It combines two types of insulin: insulin lispro, which starts working quickly, and insulin lispro protamine, which works more slowly. This mix helps control blood sugar levels throughout the day and night.
Humalog Mix50 primarily works by regulating glucose metabolism. This insulin formulation lowers blood glucose levels in two main ways: it encourages skeletal muscle and fat tissue to take up glucose, and it reduces glucose production in the liver. By improving how glucose is used in the body and decreasing excess glucose production, Humalog Mix50 effectively helps manage blood sugar levels for people with diabetes.
Humalog Mix50 starts working within 15 minutes after injection. It is designed to control high blood sugar quickly and has a shorter duration of action compared to regular insulin. For best results, it should be administered within 15 minutes before a meal.
Common side effects of Humalog Mix50 include low blood sugar, reactions at the injection site, skin thickening or pits at the injection site, weight gain, swelling in the hands or feet, itching, and rash.
Humalog Mix50 should be stored in the refrigerator at 36° to 46°F (2° to 8°C). Do not freeze it. If stored at room temperature below 86°F (30°C), use within 28 days and discard any unused portion.
The dosage of Humalog Mix50 varies depending on individual blood sugar levels, dietary habits, and physical activity. Your doctor will determine the specific dose based on your needs.
Yes, Humalog Mix50 can be used during pregnancy. It does not significantly pass into breast milk and is generally considered safe for both the mother and the baby.
To properly inject Humalog Mix50, start by selecting a clean, dry area on your abdomen or thigh and clean it with an alcohol swab. Prepare the cartridge or pen to ensure it contains Humalog Mix50 and is loaded correctly. Attach a new needle to the pen or syringe and remove the cap. If using a pen, prime the needle by dispensing a small amount of insulin to remove air bubbles. Pinch the skin slightly, insert the needle at a 90-degree angle, and press the button on the pen or syringe to inject the insulin. Hold the needle in place for a few seconds to ensure the full dose is delivered, then withdraw it and dispose of the needle safely in a sharps container.
If you miss a dose of Humalog Mix50 and more than 1 hour has passed since you ate, skip the missed dose and wait until your next scheduled dose. Do not double up on doses to make up for a missed one.
Humalog Mix50 can be used with other diabetes medications, but it should never be mixed in the same syringe with other insulin products. Additionally, it should not be used in an insulin pump. Always keep a quick source of sugar, such as glucose tablets, hard candy, or juice, on hand to treat low blood sugar.
Using Humalog Mix50 with alcohol can increase the risk of low blood sugar (hypoglycemia). Alcohol can affect blood sugar levels and may interfere with your ability to manage your diabetes effectively.
To avoid hypoglycemia while using Humalog Mix50, regularly monitor your blood sugar levels and avoid skipping or delaying meals and snacks. Always measure and take your medication as prescribed and adjust it if you increase physical activity. If you consume alcohol, do so with a meal or snack to prevent low blood sugar.
If you experience an allergic reaction to Humalog Mix50, such as rash, itching, swelling, or difficulty breathing, stop using the medication immediately and seek medical help.
You should monitor your blood sugar levels as frequently as your healthcare provider recommends, which is often multiple times a day. Regular monitoring helps you determine how much insulin to take at mealtimes or before bed.
Symptoms of a Humalog Mix50 overdose may include severe hypoglycemia (low blood sugar), which can cause dizziness, sweating, confusion, headache, blurred vision, shakiness, and fast heartbeat.
To determine if your Humalog Mix50 cartridge is expired, check the expiration date printed on the packaging. Typically, once opened, insulin cartridges expire 28 days later. If the cartridge has been stored properly and has been open for more than 28 days, it should be discarded, even if the expiration date has not yet passed.
To properly dispose of used Humalog Mix50 cartridges, place them in a designated sharps container or a heavy-duty plastic container with a tight-fitting lid. Do not throw them in regular trash or recycling bins.
If you’re looking for alternatives to Humalog Mix50, there are several other insulin options available. For rapid-acting insulin, you might consider Novolog (insulin aspart) or Apidra (insulin glulisine). For long-acting insulin, Lantus (insulin glargine) and Levemir (insulin detemir) are commonly used. Additionally, other mixed insulin products, such as NovoLog Mix 70/30, can be considered.

Disclaimer

Buy Canadian Insulin provides educational information about medications and health conditions for informational purposes only. This content is not intended to replace professional medical advice, diagnosis, or treatment. Prescription medications require valid prescription review and processing through participating pharmacy partners. Product availability, pricing, and shipping timelines may vary. Consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

Price Match Guarantee

Price Match Guarantee

We’re dedicated to offering you the best value on every medication. If you discover a lower price on the same product at another verified Canadian online pharmacy, we’ll match it—so you can shop with confidence knowing you’re always getting a fair deal.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online provider with a verifiable address.
  • The competitor’s price must be active and current (not from past or upcoming promotions).
  • The product must match exactly in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be made before completing your order—we cannot adjust prices after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone before checkout.

Note: Price matching does not currently apply to Mounjaro®, Ozempic®, or Saxenda®. This policy may be revised in the future.

Kenneth Fill, PharmD, MBA

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.

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