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Have a prescription? Buy Xenical from Canada and enjoy a host of benefits, including:

  • Cost Savings: Buy Xenical at prices significantly lower than in the US
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  • Express Shipping: Reliable and efficient delivery across the US
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  • SAVE 10% on first order with coupon code: FIRST10
Xenical (orlistat)

Starting from $199

Select product strength & quantity:

Prescription Required.

Product of Canada.

Express Ships from Canada.

Prescription Required.
Product of Canada.
Express Ships from Canada.

What is Xenical (Orlistat)?

Xenical, also known as orlistat, is a medication used for weight loss and weight management in patients with obesity. It is recommended for use in combination with a reduced-calorie diet.

How does Xenical work?

Xenical is a reversible inhibitor of enzymes known as gastrointestinal lipases. It forms covalent bonds with the active site of gastric and pancreatic lipases located in the lumen of the stomach and small intestine. These lipases are then unable to hydrolyze triglycerides into absorbable free fatty acids and monoglycerides. This non-absorption of dietary fats results in a calorie deficit.

Dosage and How to Use

Xenical is only available in 120 mg capsules.

Xenical should be taken as one 120 mg capsule three times a day with every main meal containing dietary fat. It should be taken during the meal or up to one hour after. If a meal is skipped or contains no dietary fat, that dose of Xenical can be omitted.


Store at room temperature (25°C or 77°F) and keep the bottle tightly closed. Temperature excursions between 15°C to 30°C (59°F to 86°F) are permitted. Do not use Xenical after the given expiration date.


If a significant overdose of Xenical is ingested, the patient should be observed for 24 hours. Based on human and animal studies, the lipase-inhibiting mechanism of Xenical should be rapidly reversible.

Previous studies have shown that patients experienced no adverse events with single doses of 800 mg or three times daily dosing of 400 mg for 15 days.

Side Effects

Common side effects of Xenical are:

  • Fatty or oily stool
  • Gas with oily discharge or oily spotting
  • Urgent feeling to have a bowel movement
  • Upset stomach
  • Increased number of bowel movements

Potential serious side effects of Xenical are:

Lowered absorption of fat-soluble vitamins

  • Take a multivitamin containing fat-soluble vitamins (A, D, E, K, and beta-carotene) once daily and at least 2 hours before or after taking Xenical.

Severe liver problems

  • Stop taking Xenical and call your doctor immediately if you experience one of the following symptoms of liver problems:
    • Loss of appetite
    • Itchy skin
    • Yellowing of the skin or eyes
    • Amber-colored (dark) urine
    • Light-colored bowel movements
    • Pain in the upper right area of your stomach

Kidney problems

  • Call your doctor immediately if you experience one of the following symptoms of kidney problems:
    • Swelling (particularly of the legs and feet)
    • Minimal or no urine output
    • Frequent or painful urination
    • Blood in the urine
    • Severe pain in the back, belly, or groin
    • Loss of appetite, nausea, and vomiting

Gallbladder problems (gallstones)

  • Call your doctor immediately if you experience one of the following symptoms of gallstones:
    • Pain in the upper right area of the stomach
    • Nausea or vomiting

This is not a complete list of all the possible side effects. Please contact your doctor or pharmacist for more information.

Warnings & Precautions

Drug interactions and reduced vitamin absorption

Xenical has been shown to reduce cyclosporine plasma levels when patients are taking both drugs. Cyclosporine should be given at least 3 hours before or after Xenical to minimize the risk of drug-drug interactions.

Patients should take a multivitamin supplement that contains fat-soluble vitamins because Xenical has been shown to reduce the absorption of fat-soluble vitamins and beta-carotene. The multivitamin should be taken at least 2 hours before or after Xenical to ensure adequate absorption.

Liver injury

There have been rare reports of severe liver injury or acute hepatic failure in patients taking Xenical. Patients must immediately report any signs of liver dysfunction (loss of appetite, itchy skin, yellowing of the skin or eyes, dark urine, light-colored bowel movements, or pain in the upper right area of the stomach) to their doctor and stop taking the medication.

Increases in Urinary Oxalate

Some patients taking Xenical may experience increased levels of urinary oxalate, which may lead to oxalate nephrolithiasis and oxalate nephropathy with renal failure. Renal function should be monitored in patients at risk for renal impairment when taking Xenical. Use caution in patients with a history of hyperoxaluria or calcium oxalate nephrolithiasis.


There is an increased risk of cholelithiasis with substantial weight loss.

Drug Interactions


  • Plasma levels of cyclosporine are reduced in patients taking both Xenical and cyclosporine. If a patient is taking both medications, cyclosporine must be administered at least 3 hours before or after Xenical.

Fat-soluble vitamins

  • Xenical has been shown to limit the absorption of beta-carotene and other fat-soluble vitamins. A fat-soluble containing vitamin supplement is recommended and should be taken at least 2 hours before or after Xenical.


  • Hypothyroidism has been reported in patients that are treated with Xenical while taking levothyroxine. Patients taking both drugs should be monitored for changes in thyroid function. Levothyroxine should be administered at least 4 hours apart from Xenical.


  • Xenical can decrease vitamin K absorption and thus affect coagulation parameters in patients on chronic warfarin therapy. Patients taking both warfarin and Xenical need to have their coagulation markers monitored closely.


Xenical is contraindicated in the following scenarios:

  • Pregnancy
  • Patients with chronic malabsorption syndrome
  • Patients with cholestasis
  • Patients with known hypersensitivity to Xenical or any component of the product

Buy Xenical Online: Price & Discounts

For patients in the United States, managing weight loss with medications like Xenical can be costly, particularly without insurance coverage. The financial burden of purchasing essential drugs can be significant, impacting one’s budget.

Fortunately, Buy Canadian Insulin (BCI) offers a more affordable option. As a prescription-referral service, BCI helps Americans access cost-effective medication through a licensed Canadian pharmacy. This makes the cost of Xenical much more manageable, providing relief for those without insurance or in the coverage gap.

Discount Code

To assist patients in managing their healthcare expenses, BCI offers a special discount. By using the coupon code FIRST10, customers can enjoy a 10% discount on their Xenical order. This discount is limited to one use per customer and provides a maximum savings of $50.

Buying Xenical & Prices

Our pricing for Xenical, available in different strengths, is designed to offer significant savings. Below is a detailed pricing breakdown:

  • 120mg – 84 capsules: $199.00
  • 120mg – 168 capsules: $390.00
  • 120mg – 252 capsules: $570.00

These prices reflect the substantial savings achievable through our service compared to typical U.S. prices.

Bulk Purchase Advantages

Purchasing Xenical in bulk can lead to even greater savings. We encourage patients to consider buying up to a 90-day supply to maximize their cost efficiency. Bulk purchases not only provide convenience but also ensure significant savings over time.

Guaranteed Quality and Fast Shipping

Quality assurance and timely delivery are our top priorities. Xenical orders are expedited efficiently, with express shipping ensuring your medication arrives within 3-5 business days after processing. This swift service guarantees quick access to your weight loss treatment without unnecessary delays.

By choosing Buy Canadian Insulin for your Xenical needs, you’re opting for a service that significantly reduces the financial burden of weight loss management. This option is particularly beneficial for those without insurance, providing access to necessary treatments at much more affordable costs.

Please note that while we strive to ensure all orders are delivered promptly, external factors such as weather, climate, and political issues may occasionally impact delivery times.

Opting for BCI means choosing reliability, affordability, and quality for your healthcare needs.

Frequently Asked Questions

Xenical is a prescription medication used with a low-calorie diet to achieve and maintain weight loss in patients with obesity.

Xenical works by preventing the absorption of dietary fat in your stomach and small intestine, resulting in a more significant calorie deficit. The dietary fat is passed through your digestive system and expelled from the body.

It is not known if Xenical is safe and effective for children under 12 years of age. In patients 12 to 16 years of age, Xenical showed similar efficacy and safety to when used in adults.

Patients should not take Xenical if they are pregnant, have chronic malabsorption syndrome, have gallbladder problems, or are allergic to orlistat or other ingredients in the preparation.

Tell your doctor about every medication (prescription or over-the-counter) and supplement you are currently taking.

Before starting Xenical, tell your doctor if you have any of the following: liver problems, kidney problems, thyroid problems, an eating disorder (bulimia or anorexia), diabetes, are breastfeeding, plan on breastfeeding, are pregnant, or plan on becoming pregnant.

Xenical should be taken as one 120 mg capsule with every meal containing fat. Take Xenical exactly as your doctor recommends. If you skip a meal or the meal contains no dietary fat, then you can skip that dose of Xenical.

If you are taking a multivitamin containing fat-soluble vitamins, take it at least 2 hours before or after treatment.

If you are taking cyclosporine, take it at least 3 hours before or after Xenical.

If you are taking levothyroxine, take it at least 4 hours apart from Xenical.

Xenical should be stored at room temperature (59°F to 86°F or 15°C to 30°C) in a tightly closed container. Do not use the medication after the expiration date listed on the bottle.

The most common side effects of Xenical are fatty stool, gas with an oily discharge, oily spotting, urgent feeling to have a bowel movement, and upset stomach.

Yes, the generic version of the drug is orlistat.

If it is still within one hour of the intended meal, then you may take the missed dose. Xenical can be taken up to one hour after a meal. If it has been longer than one hour after the meal, skip the dose and continue the dosage schedule at the next meal.

You should not take Xenical if you are pregnant or plan on becoming pregnant. Notify your doctor immediately if you become pregnant or plan on becoming pregnant.

You should eat a balanced, reduced-calorie diet, where 30% of the calories come from dietary fat. The total daily intake of carbohydrates, protein, and fats should be spread across three main meals.

No, you do not have to take your dose of Xenical if you skip the meal or have a meal containing no dietary fat.

Xenical contains 120 mg of orlistat, while Alli contains 60 mg of orlistat. They have the same active ingredient, but Xenical is a stronger medication. Another significant difference is Xenical is only available as a prescription, and Alli is available over-the-counter.

The amount of weight loss you will experience depends on multiple factors. In order to maximize weight loss, it is essential to maintain eating in a calorie deficit, exercise regularly, and take Xenical precisely as directed by your doctor.