Buy Zyban from Canada at LOWEST PRICES
from$148.95
$824
Zyban Bupropion Hydrochloride
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Product of Canada
Secure Payment MethodsSecure checkout with Visa & Mastercard
Visa and Mastercard
from$49.99
$287
Bupropion SR Bupropion HCl
Select product strength & quantity:
Contrave Bupropion Hydrochloride, Naltrexone Hydrochloride
Select product strength & quantity:
Wellbutrin XL Bupropion Hydrochloride XL
Select product strength & quantity:
Wellbutrin XL Bupropion Hydrochloride XL
Select product strength & quantity:
Bupropion XL (Generic) Bupropion Hydrochloride XL
Select product strength & quantity:
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Product of Canada

What is Zyban?

Zyban (bupropion) is a prescription treatment that helps people stop smoking. It contains bupropion, which works in the brain to reduce the craving for nicotine. Nicotine is the part of tobacco that causes addiction and makes quitting difficult.

Zyban works best when used with a stop-smoking program. These programs might include support groups, counseling, or advice to help you stay on track. Combining Zyban with support increases your chances of quitting for good.

Some people should not take Zyban. This includes anyone who has had seizures or eating disorders such as anorexia or bulimia. It is also unsafe for individuals who are already taking another product containing bupropion. Zyban is also not safe for people who suddenly stop drinking alcohol or using certain calming drugs.

Before using Zyban, talk to your doctor or pharmacist. They can help you decide if Zyban is safe for you and give you tips to support your quit-smoking journey.

Quitting smoking is one of the best steps you can take for your health. It lowers your risk of lung problems, heart disease, and some types of cancer.

How Does Zyban Work?

Zyban helps people quit smoking by changing how certain chemicals work in the brain. It affects two primary brain chemicals, dopamine and norepinephrine.

These chemicals play a role in mood, energy, and cravings. By balancing these chemicals, Zyban helps reduce the urge to smoke and makes withdrawal symptoms feel less intense.

Zyban does not affect serotonin, a brain chemical involved in mood regulation. It also does not block an enzyme called monoamine oxidase, which is linked to how some other drugs work.

Zyban Dose and Usage

Take Zyban in 150 mg sustained-release tablets by swallowing them whole. Start taking Zyban before your planned “quit date”, usually about one week before you stop smoking.

Begin the Zyban dose at a low level and increase it gradually to reduce the risk of side effects. Take Zyban with or without food, but never crush, split, or chew the tablets.

Dosage Form and Strengths of Zyban

Zyban is available as a 150 mg sustained-release tablet. Each tablet is purple, round, and film-coated, and it is designed to release the medication slowly in your body.

This helps maintain a steady level of the drug throughout the day. The Zyban dose is carefully adjusted to reduce the chance of side effects such as seizures.

How to Take Zyban?

  • Start taking Zyban about one week before your planned quit date.
  • For the first three days, take one 150 mg tablet once each day.
  • After the first three days, take 150 mg twice a day, with at least eight hours between each dose.
  • Do not take more than 300 mg of Zyban in a single day.
  • You can take Zyban with or without food.
  • Swallow each tablet whole. Do not crush, cut, or chew the tablets.
  • Try to avoid taking Zyban close to bedtime to help prevent trouble sleeping.
  • If you miss a dose, skip it and take the next tablet at the regular time. Do not take two doses at the same time.
  • Continue taking Zyban for 7 to 12 weeks, or as advised by your doctor.
  • Speak with your doctor if you think you need to take Zyban for more than twelve weeks.
  • Your doctor may recommend using Zyban together with a nicotine patch for better results.
  • If you have liver or kidney problems, your Zyban dose may need to be adjusted.
  • Do not take Zyban with certain medications, such as monoamine oxidase (MAO) inhibitors like linezolid or methylene blue.
  • Be sure to inform your doctor about all your health conditions before starting Zyban.
  • Always follow the instructions on your prescription label and take the medication exactly as advised by your doctor.

Zyban Side Effects

Some of the most common Zyban side effects include trouble sleeping, dry mouth, nausea, dizziness, and constipation. While these effects are usually mild, some people may experience severe reactions.

Severe Zyban tablet side effects may include seizures, mood changes, or allergic reactions. Consult your doctor if any side effects bother you or if you experience any new or unusual symptoms.

Common Side Effects

These Zyban side effects are usually mild and go away over time:

  • Trouble sleeping
  • Dry mouth
  • Nausea
  • Constipation
  • Dizziness
  • Feeling anxious
  • Stuffy nose
  • Joint aches
  • Loss of appetite
  • Shaking or tremors

Severe Side Effects

Some Zyban tablet side effects may be serious and need immediate medical attention:

  • Allergic reactions such as rash, hives, or swelling of the face, lips, tongue, or throat
  • Seizures
  • High blood pressure
  • Mood changes such as depression, anxiety, irritability, confusion, or thoughts of self-harm
  • Hallucinations or sudden behavior changes
  • Eye pain or vision changes like blurry vision or seeing halos
  • Redness, peeling, or blistering of the skin, including inside the mouth

Warnings and Precautions for Zyban

Zyban helps people stop smoking, but it has some important warnings and precautions. Zyban contains the same ingredient as some antidepressants, which means it can affect the brain and mood.

Even though it is not used to treat depression, it may still cause serious mental health side effects, especially in younger people.

Some of these side effects include suicidal thoughts, changes in behavior, or even seizures. Patients, families, and caregivers should closely monitor for any unusual changes, especially when starting or adjusting the dose.

  • Zyban contains the same ingredient as some depression medications. It may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults.
  • People taking Zyban should be watched closely for signs of worsening mood, unusual behavior, or thoughts of hurting themselves.
  • Families and caregivers should monitor the person taking Zyban daily and notify a doctor immediately if they notice any changes in mood, increased anger, or unusual behavior.
  • Zyban may cause serious mood or mental health problems during smoking cessation, including depression, paranoia, hallucinations, panic, or suicidal thoughts.
  • These mental health symptoms can happen in people with or without a history of mental illness, so all patients need careful monitoring.
  • If the person taking Zyban becomes agitated, sad, or behaves in a way that is not normal for them, they should stop the medication and contact a doctor right away.
  • In some people, mental health symptoms went away after stopping Zyban, but in others, they continued, so ongoing support is important.
  • Zyban can cause seizures, especially if taken in high doses or by people who have risk factors for seizures.
  • Do not take more than 300 mg of Zyban a day, and stop taking it if you have a seizure.
  • Do not use Zyban if you have a seizure disorder, have or had an eating disorder like anorexia or bulimia, or if you suddenly stop drinking alcohol or taking certain medications like sleeping pills or anti-seizure drugs.
  • Tell your doctor about all medications you take, because some can make seizures more likely when taken with Zyban.
  • Doctors should give the smallest number of Zyban tablets needed to help prevent overdose.

Zyban Drug Interactions

Some drug combinations can raise the risk of serious side effects or make Zyban less effective.

Always inform your doctor about all medications and supplements you take to avoid potential harmful interactions.

Here are some of the possible interactions with Zyban:

  • Other drugs that contain bupropion like Wellbutrin
  • Methylene blue (injected into a vein)
  • Linezolid
  • MAOIs (Marplan, Nardil, Parnate, Azilect, Carbex, Eldepryl)
  • Alcohol
  • Nicotine
  • Tramadol
  • Tamoxifen
  • Theophylline
  • Warfarin
  • Digoxin
  • Clopidogrel
  • Ticlopidine
  • Cyclophosphamide
  • Thiotepa
  • Procarbazine
  • Furazolidone
  • Isoniazid
  • Cimetidine
  • Orphenadrine
  • Steroids: cortisone, prednisone
  • Stimulants for attention, weight loss, or alertness
  • Drugs for anxiety or sleep
  • Drugs for depression or psychotic disorders
  • Parkinsons drugs (levodopa, amantadine)
  • HIV or AIDS drugs (ritonavir, lopinavir, efavirenz, nelfinavir)
  • Seizure drugs (phenobarbital, phenytoin, carbamazepine)
  • Blood pressure drugs (propranolol, metoprolol)
  • Heart rhythm drugs (flecainide, propafenone)

Alternative to Zyban

If you are considering alternatives to Zyban for smoking cessation, several options are available.

These alternatives work in different ways to help individuals quit smoking. It is important to consult with your healthcare provider to determine the most suitable option for your needs.

Here are some alternatives to consider:

  • Wellbutrin (bupropion)
  • Nicorette (nicotine)
  • Nicoderm CQ (nicotine)
  • Habitrol (nicotine)
  • Chantix (varenicline)
  • Catapres (clonidine)
  • Nortriptyline

Cost & Ordering Information

Buy Zyban Through Buy Canadian Insulin

Buy Canadian Insulin helps patients access Zyban through participating pharmacy partners.

Pricing may vary depending on the prescribed strength, quantity selected, supplier availability, and participating pharmacy partner pricing policies.

Some patients may find pricing through participating pharmacy partners that differs from certain U.S. retail pharmacy prices.

Available services may include:

  • Zyban pricing options based on quantity selected
  • Prescription processing through participating pharmacy partners
  • Multiple quantity options, subject to prescription authorization
  • Shipping options available to eligible U.S. delivery locations
  • Customer support assistance by phone, email, or live chat
  • Online and phone ordering options

A valid prescription is required to purchase Zyban.

All prescription orders are reviewed and processed in accordance with applicable pharmacy and regulatory requirements.

Shipping timelines may vary based on prescription verification, product availability, destination location, and carrier services.

First-Time Customer Savings

Eligible first-time customers may use coupon code FIRST10 during checkout for qualifying orders, subject to current promotional terms and conditions.

How to Order Zyban

Step 1: Search for Zyban on the website and select the prescribed strength and quantity.

Step 2: Add Zyban to your cart and complete checkout by entering your contact information, shipping address, and payment details.

Step 3: Submit a valid prescription using one of the approved methods below.

How to Submit Your Zyban Prescription

Patients may submit a prescription through any of the following methods:

Upload: Through the prescription upload feature during checkout

Email: info@buycanadianinsulin.com

Fax: 1-888-234-1275

Prescription requirements and processing times may vary depending on pharmacy partner requirements.

Customer Support

For questions regarding Zyban availability, prescription submission, order status, or shipping information, contact:

Phone: 1-888-525-1815

Fax: 1-888-234-1275

Email: info@buycanadianinsulin.com

Hours of Operation

Monday–Friday: 7:00 AM – 10:00 PM CST

Saturday–Sunday: 9:00 AM – 5:00 PM CST

Business Address

Buy Canadian Insulin

1026 Manitoba Avenue, Suite 1001

Selkirk, MB R1A 4M2

Canada

About Buy Canadian Insulin

Buy Canadian Insulin works with participating pharmacy partners to help patients access Zyban and other prescription medications.

Product availability, pricing, fulfillment location, and shipping timelines may vary depending on supplier inventory, participating pharmacy partner availability, and destination location.

Some Zyban orders may be fulfilled through licensed pharmacy partners located in Canada or other international fulfillment locations, depending on product availability and pharmacy partner sourcing.

Frequently Asked Questions

Zyban is used to help people stop smoking by reducing withdrawal symptoms and the urge to smoke. It is also prescribed for depression in some cases.
Zyban and Wellbutrin are the same type of medication, but are used for different purposes. Zyban is prescribed to help quit smoking, while Wellbutrin is used to treat depression and seasonal affective disorder. Both work by increasing the levels of norepinephrine and dopamine in the brain.
To stop smoking with Zyban, start treatment while still smoking and set a target stop date within the first two weeks. The usual starting dose is 150 mg once daily for three days, followed by an increase to 150 mg twice daily for at least 7 weeks.
Yes, Zyban can cause changes in behavior, including depression, suicidal thoughts, or actions. These symptoms may occur during treatment or after stopping the medication.
Common side effects of Zyban include insomnia, dry mouth, headache, dizziness, and nausea. Serious side effects can include changes in mood, suicidal thoughts, and seizures.
Zyban is not typically associated with weight gain. Studies have shown that individuals taking Zyban may gain less weight compared to those on a placebo. Women treated with Zyban gained an average of 8.14 pounds less over 18 months. However, the effect on weight may vary between individuals.
No, Zyban is not a controlled substance. It is a prescription medication used to help with smoking cessation.
You should not take Zyban with MAOIs, other bupropion-containing drugs like Wellbutrin, linezolid, or methylene blue. Avoid alcohol, as it may increase the risk of seizures. Zyban can also interact with medications for anxiety, sleep, blood pressure, depression, seizures, HIV, Parkinson’s disease, heart rhythm issues, and certain antibiotics or steroids. Always tell your doctor about all treatments, supplements, or substances you use before starting Zyban.
Zyban is fully cleared from the body within about four days after the last dose.
Zyban does not work straight away. Most people start noticing changes in their smoking habits within 2 weeks, but this can vary.

Disclaimer

Buy Canadian Insulin provides educational information about medications and health conditions for informational purposes only. This content is not intended to replace professional medical advice, diagnosis, or treatment. Prescription medications require valid prescription review and processing through participating pharmacy partners. Product availability, pricing, and shipping timelines may vary. Consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

5 Star Excellence award from Shopper Approved for collecting at least 100 5 star reviews

Have a prescription?

Order Zyban online today and enjoy a host of benefits, including:

  • Cost Savings: Buy Zyban at significantly lower prices than in the US prices
  • Bulk Order Discounts: Save more on bulk orders of Zyban (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped right to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-525-1815
  • SAVE 10% on first order with coupon code: FIRST10

Price Match Guarantee

Price Match Guarantee

We’re dedicated to offering you the best value on every medication. If you discover a lower price on the same product at another verified Canadian online pharmacy, we’ll match it—so you can shop with confidence knowing you’re always getting a fair deal.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online provider with a verifiable address.
  • The competitor’s price must be active and current (not from past or upcoming promotions).
  • The product must match exactly in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be made before completing your order—we cannot adjust prices after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone before checkout.

Note: Price matching does not currently apply to Mounjaro®, Ozempic®, or Saxenda®. This policy may be revised in the future.

Kenneth Fill, PharmD, MBA

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.